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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Pharmacogenomics. 2013 Jan;14(1):35–45. doi: 10.2217/pgs.12.180

Figure 1. Study design for carbamazepine pathway pharmacogenomics.

Figure 1

SNPs indicated in bold have been shown to be of functional relevance.

AUC: Area under the curve; CBZ: Carbamazepine; CBZ-diol: Carbamazepine-10,11-trans dihydrodiol; CBZ-E: Carbamazepine 10-11 epoxide; LD: Linkage disequilibrium; MAF: Minimum allele frequency; Nonsyn: Nonsynonymous; PK: Pharmacokinetic; Syn: Synonymous.