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. 2013 Feb;61(2):630–638. doi: 10.1016/j.cyto.2012.11.014

Fig. 4.

Fig. 4

Activity of human, mouse and porcine recombinant CSF-1 on feline CSF-1R expressed in Ba/F3 cells. An MTT cell viability assay was used to assess the biological activity of recombinant human, mouse and porcine CSF-1 in the feline CSF-1R. (A) Both human and mouse CSF-1 are biologically active on the feline CSF-1R, with mouse CSF-1 demonstrating reduced activity compared to human CSF-1. (B) Comparing the effects of human and porcine CSF-1 on the feline CSF-1R demonstrates that these recombinant proteins are identical in their activation.