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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Hypertension. 2013 Mar;61(3):673–680. doi: 10.1161/HYPERTENSIONAHA.111.00241

Figure 2.

Figure 2

Validation of an independent functional intrarenal renin-angiotensin system in uninephrectomized conscious dogs. Estimated renal plasma flow (ERPF; Panel A), glomerular filtration rate (GFR; Panel B), urine flow rate (UVOL; Panel C) and urinary Na+ excretion (UNaV; Panel D) in response to low-dose intrarenal arterial infusion of Ang receptor blocker saralasin (0.07 μg/kg/min). Numbers on abscissa represent 20 min clearance periods. Adapted from Levens NR et al. Endocrinology. 1983:112:43–49 with permission.