Skip to main content
Clinical Microbiology Reviews logoLink to Clinical Microbiology Reviews
. 1989 Apr;2(Suppl):S11–S17. doi: 10.1128/cmr.2.suppl.s11

Interaction of complement with Neisseria meningitidis and Neisseria gonorrhoeae.

P Densen 1
PMCID: PMC358071  PMID: 2497954

Full text

PDF
S11

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beatty D. W., Ryder C. R., Heese H. D. Complement abnormalities during an epidemic of group B meningococcal infection in children. Clin Exp Immunol. 1986 Jun;64(3):465–470. [PMC free article] [PubMed] [Google Scholar]
  2. Brown E. J., Joiner K. A., Cole R. M., Berger M. Localization of complement component 3 on Streptococcus pneumoniae: anti-capsular antibody causes complement deposition on the pneumococcal capsule. Infect Immun. 1983 Jan;39(1):403–409. doi: 10.1128/iai.39.1.403-409.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. DeVoe I. W. The meningococcus and mechanisms of pathogenicity. Microbiol Rev. 1982 Jun;46(2):162–190. doi: 10.1128/mr.46.2.162-190.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Densen P., Gulati S., Rice P. A. Specificity of antibodies against Neisseria gonorrhoeae that stimulate neutrophil chemotaxis. Role of antibodies directed against lipooligosaccharides. J Clin Invest. 1987 Jul;80(1):78–87. doi: 10.1172/JCI113067. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Densen P., MacKeen L. A., Clark R. A. Dissemination of gonococcal infection is associated with delayed stimulation of complement-dependent neutrophil chemotaxis in vitro. Infect Immun. 1982 Nov;38(2):563–572. doi: 10.1128/iai.38.2.563-572.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Densen P., McRill C. M., Ross S. C. Assembly of the membrane attack complex promotes decay of the alternative pathway C3 convertase on Neisseria gonorrhoeae. J Immunol. 1988 Dec 1;141(11):3902–3909. [PubMed] [Google Scholar]
  7. Densen P., Weiler J. M., Griffiss J. M., Hoffmann L. G. Familial properdin deficiency and fatal meningococcemia. Correction of the bactericidal defect by vaccination. N Engl J Med. 1987 Apr 9;316(15):922–926. doi: 10.1056/NEJM198704093161506. [DOI] [PubMed] [Google Scholar]
  8. Ellison R. T., 3rd, Kohler P. F., Curd J. G., Judson F. N., Reller L. B. Prevalence of congenital or acquired complement deficiency in patients with sporadic meningocococcal disease. N Engl J Med. 1983 Apr 21;308(16):913–916. doi: 10.1056/NEJM198304213081601. [DOI] [PubMed] [Google Scholar]
  9. Fearon D. T., Austen K. F. Properdin: binding to C3b and stabilization of the C3b-dependent C3 convertase. J Exp Med. 1975 Oct 1;142(4):856–863. doi: 10.1084/jem.142.4.856. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Fearon D. T. Continuing medical education. This continuing medical education self-assessment program is sponsored by the American Academy of Allergy and Immunology and supported by a grant-in-aid from Fisons Corporation. J Allergy Clin Immunol. 1983 Jun;71(6):520–532. doi: 10.1016/0091-6749(83)90431-1. [DOI] [PubMed] [Google Scholar]
  11. Fearon D. T. Regulation by membrane sialic acid of beta1H-dependent decay-dissociation of amplification C3 convertase of the alternative complement pathway. Proc Natl Acad Sci U S A. 1978 Apr;75(4):1971–1975. doi: 10.1073/pnas.75.4.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Frank M. M., Joiner K., Hammer C. The function of antibody and complement in the lysis of bacteria. Rev Infect Dis. 1987 Sep-Oct;9 (Suppl 5):S537–S545. doi: 10.1093/clinids/9.supplement_5.s537. [DOI] [PubMed] [Google Scholar]
  13. Goldschneider I., Gotschlich E. C., Artenstein M. S. Human immunity to the meningococcus. I. The role of humoral antibodies. J Exp Med. 1969 Jun 1;129(6):1307–1326. doi: 10.1084/jem.129.6.1307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Greenwood B. M., Onyewotu I. I., Whittle H. C. Complement and meningococcal infection. Br Med J. 1976 Apr 3;1(6013):797–799. doi: 10.1136/bmj.1.6013.797. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Griffiss J. M. Bactericidal activity of meningococcal antisera. Blocking by IgA of lytic antibody in human convalescent sera. J Immunol. 1975 Jun;114(6):1779–1784. [PubMed] [Google Scholar]
  16. Griffiss J. M., Goroff D. K. IgA blocks IgM and IgG-initiated immune lysis by separate molecular mechanisms. J Immunol. 1983 Jun;130(6):2882–2885. [PubMed] [Google Scholar]
  17. Harriman G. R., Esser A. F., Podack E. R., Wunderlich A. C., Braude A. I., Lint T. F., Curd J. G. The role of C9 in complement-mediated killing of Neisseria. J Immunol. 1981 Dec;127(6):2386–2390. [PubMed] [Google Scholar]
  18. Harriman G. R., Podack E. R., Braude A. I., Corbeil L. C., Esser A. F., Curd J. G. Activation of complement by serum-resistant Neisseria gonorrhoeae. Assembly of the membrane attack complex without subsequent cell death. J Exp Med. 1982 Oct 1;156(4):1235–1249. doi: 10.1084/jem.156.4.1235. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Hoffman T. A., Edwards E. A. Group-specific polysaccharide antigen and humoral antibody response in disease due to Neisseria meningitidis. J Infect Dis. 1972 Dec;126(6):636–644. doi: 10.1093/infdis/126.6.636. [DOI] [PubMed] [Google Scholar]
  20. Hostetter M. K., Krueger R. A., Schmeling D. J. The biochemistry of opsonization: central role of the reactive thiolester of the third component of complement. J Infect Dis. 1984 Nov;150(5):653–661. doi: 10.1093/infdis/150.5.653. [DOI] [PubMed] [Google Scholar]
  21. Ingwer I., Petersen B. H., Brooks G. Serum bactericidal action and activation of the classic and alternate complement pathways by Neisseria gonorrhoeae. J Lab Clin Med. 1978 Aug;92(2):211–220. [PubMed] [Google Scholar]
  22. Jarvis G. A., Vedros N. A. Sialic acid of group B Neisseria meningitidis regulates alternative complement pathway activation. Infect Immun. 1987 Jan;55(1):174–180. doi: 10.1128/iai.55.1.174-180.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Jennings H. J. Capsular polysaccharides as human vaccines. Adv Carbohydr Chem Biochem. 1983;41:155–208. doi: 10.1016/s0065-2318(08)60058-x. [DOI] [PubMed] [Google Scholar]
  24. Joiner K. A., Scales R., Warren K. A., Frank M. M., Rice P. A. Mechanism of action of blocking immunoglobulin G for Neisseria gonorrhoeae. J Clin Invest. 1985 Nov;76(5):1765–1772. doi: 10.1172/JCI112167. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Joiner K. A., Warren K. A., Brown E. J., Swanson J., Frank M. M. Studies on the mechanism of bacterial resistance to complement-mediated killing. IV. C5b-9 forms high molecular weight complexes with bacterial outer membrane constituents on serum-resistant but not on serum-sensitive Neisseria gonorrhoeae. J Immunol. 1983 Sep;131(3):1443–1451. [PubMed] [Google Scholar]
  26. Joiner K. A., Warren K. A., Hammer C., Frank M. M. Bactericidal but not nonbactericidal C5b-9 is associated with distinctive outer membrane proteins in Neisseria gonorrhoeae. J Immunol. 1985 Mar;134(3):1920–1925. [PubMed] [Google Scholar]
  27. Joiner K. A., Warren K. A., Tam M., Frank M. M. Monoclonal antibodies directed against gonococcal protein I vary in bactericidal activity. J Immunol. 1985 May;134(5):3411–3419. [PubMed] [Google Scholar]
  28. Lambris J. D., Müller-Eberhard H. J. The multifunctional role of C3: structural analysis of its interactions with physiological ligands. Mol Immunol. 1986 Nov;23(11):1237–1242. doi: 10.1016/0161-5890(86)90157-4. [DOI] [PubMed] [Google Scholar]
  29. Merino J., Rodriguez-Valverde V., Lamelas J. A., Riestra J. L., Casanueva B. Prevalence of deficits of complement components in patients with recurrent meningococcal infections. J Infect Dis. 1983 Aug;148(2):331–331. doi: 10.1093/infdis/148.2.331. [DOI] [PubMed] [Google Scholar]
  30. Nicholson A., Lepow I. H. Host defense against Neisseria meningitidis requires a complement-dependent bactericidal activity. Science. 1979 Jul 20;205(4403):298–299. doi: 10.1126/science.451601. [DOI] [PubMed] [Google Scholar]
  31. Petersen B. H., Lee T. J., Snyderman R., Brooks G. F. Neisseria meningitidis and Neisseria gonorrhoeae bacteremia associated with C6, C7, or C8 deficiency. Ann Intern Med. 1979 Jun;90(6):917–920. doi: 10.7326/0003-4819-90-6-917. [DOI] [PubMed] [Google Scholar]
  32. Rasmussen J. M., Brandslund I., Teisner B., Isager H., Svehag S. E., Maarup L., Willumsen L., Rønne-Rasmussen J. O., Permin H., Andersen P. L. Screening for complement deficiencies in unselected patients with meningitis. Clin Exp Immunol. 1987 May;68(2):437–445. [PMC free article] [PubMed] [Google Scholar]
  33. Ratnoff W. D., Fearon D. T., Austen K. F. The role of antibody in the activation of the alternative complement pathway. Springer Semin Immunopathol. 1983;6(4):361–371. doi: 10.1007/BF02116280. [DOI] [PubMed] [Google Scholar]
  34. Rice P. A., Kasper D. L. Characterization of serum resistance of Neisseria gonorrhoeae that disseminate. Roles of blocking antibody and gonococcal outer membrane proteins. J Clin Invest. 1982 Jul;70(1):157–167. doi: 10.1172/JCI110589. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Rice P. A., Vayo H. E., Tam M. R., Blake M. S. Immunoglobulin G antibodies directed against protein III block killing of serum-resistant Neisseria gonorrhoeae by immune serum. J Exp Med. 1986 Nov 1;164(5):1735–1748. doi: 10.1084/jem.164.5.1735. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Ross S. C., Berberich H. M., Densen P. Natural serum bactericidal activity against Neisseria meningitidis isolates from disseminated infections in normal and complement-deficient hosts. J Infect Dis. 1985 Dec;152(6):1332–1335. doi: 10.1093/infdis/152.6.1332. [DOI] [PubMed] [Google Scholar]
  37. Ross S. C., Densen P. Complement deficiency states and infection: epidemiology, pathogenesis and consequences of neisserial and other infections in an immune deficiency. Medicine (Baltimore) 1984 Sep;63(5):243–273. [PubMed] [Google Scholar]
  38. Ross S. C., Densen P. Opsonophagocytosis of Neisseria gonorrhoeae: interaction of local and disseminated isolates with complement and neutrophils. J Infect Dis. 1985 Jan;151(1):33–41. doi: 10.1093/infdis/151.1.33. [DOI] [PubMed] [Google Scholar]
  39. Ross S. C., Rosenthal P. J., Berberich H. M., Densen P. Killing of Neisseria meningitidis by human neutrophils: implications for normal and complement-deficient individuals. J Infect Dis. 1987 Jun;155(6):1266–1275. doi: 10.1093/infdis/155.6.1266. [DOI] [PubMed] [Google Scholar]
  40. Schoolnik G. K., Buchanan T. M., Holmes K. K. Gonococci causing disseminated gonococcal infection are resistant to the bactericidal action of normal human sera. J Clin Invest. 1976 Nov;58(5):1163–1173. doi: 10.1172/JCI108569. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Sjöholm A. G., Braconier J. H., Söderström C. Properdin deficiency in a family with fulminant meningococcal infections. Clin Exp Immunol. 1982 Nov;50(2):291–297. [PMC free article] [PubMed] [Google Scholar]
  42. Spink W. W., Keefer C. S. STUDIES OF GONOCOCCAL INFECTION. II. THE BACTERIOLYTIC POWER OF THE WHOLE DEFIBRINATED BLOOD OF PATIENTS WITH GONOCOCCAL ARTHRITIS. J Clin Invest. 1937 Mar;16(2):177–183. doi: 10.1172/JCI100845. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Swanson J., Goldschneider I. The serum bactericidal system: ultrastructural changes in Neisseria meningitidis exposed to normal rat serum. J Exp Med. 1969 Jan 1;129(1):51–79. doi: 10.1084/jem.129.1.51. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. Söderström C., Braconier J. H., Danielsson D., Sjöholm A. G. Bactericidal activity for Neisseria meningitidis in properdin-deficient sera. J Infect Dis. 1987 Jul;156(1):107–112. doi: 10.1093/infdis/156.1.107. [DOI] [PubMed] [Google Scholar]
  45. Zollinger W. D., Mandrell R. E. Importance of complement source in bactericidal activity of human antibody and murine monoclonal antibody to meningococcal group B polysaccharide. Infect Immun. 1983 Apr;40(1):257–264. doi: 10.1128/iai.40.1.257-264.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Zwahlen A., Waldvogel F. A. Magnitude of bacteremia and complement activation during Neisseria meningitidis infection: study of two co-primary cases with different clinical presentations. Eur J Clin Microbiol. 1984 Oct;3(5):439–441. doi: 10.1007/BF02017367. [DOI] [PubMed] [Google Scholar]

Articles from Clinical Microbiology Reviews are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES