Full text
PDF







Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Buchanan T. M. Antigenic heterogeneity of gonococcal pili. J Exp Med. 1975 Jun 1;141(6):1470–1475. doi: 10.1084/jem.141.6.1470. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Buchanan T. M., Swanson J., Holmes K. K., Kraus S. J., Gotschlich E. C. Quantitative determination of antibody to gonococcal pili. Changes in antibody levels with gonococcal infection. J Clin Invest. 1973 Nov;52(11):2896–2909. doi: 10.1172/JCI107486. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Densen P., Mandell G. L. Gonococcal interactions with polymorphonuclear neutrophils: importance of the phagosome for bactericidal activity. J Clin Invest. 1978 Dec;62(6):1161–1171. doi: 10.1172/JCI109235. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dilworth J. A., Hendley J. O., Mandell G. L. Attachment and ingestion of gonococci human neutrophils. Infect Immun. 1975 Mar;11(3):512–516. doi: 10.1128/iai.11.3.512-516.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Duckworth M., Jackson D., Zak K., Heckels J. E. Structural variations in pili expressed during gonococcal infection. J Gen Microbiol. 1983 May;129(5):1593–1596. doi: 10.1099/00221287-129-5-1593. [DOI] [PubMed] [Google Scholar]
- Gibbs D. L., Roberts R. B. The interaction in vitro between human polymorphonuclear leukocytes and Neisseria gonorrhoeae cultivated in the chick embryo. J Exp Med. 1975 Jan 1;141(1):155–171. doi: 10.1084/jem.141.1.155. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Goldschneider I., Gotschlich E. C., Artenstein M. S. Human immunity to the meningococcus. II. Development of natural immunity. J Exp Med. 1969 Jun 1;129(6):1327–1348. doi: 10.1084/jem.129.6.1327. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gubish E. R., Jr, Chen K. C., Buchanan T. M. Attachment of gonococcal pili to lectin-resistant clones of Chinese hamster ovary cells. Infect Immun. 1982 Jul;37(1):189–194. doi: 10.1128/iai.37.1.189-194.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hagblom P., Segal E., Billyard E., So M. Intragenic recombination leads to pilus antigenic variation in Neisseria gonorrhoeae. Nature. 1985 May 9;315(6015):156–158. doi: 10.1038/315156a0. [DOI] [PubMed] [Google Scholar]
- Heckels J. E., Blackett B., Everson J. S., Ward M. E. The influence of surface charge on the attachment of Neisseria gonorrhoeae to human cells. J Gen Microbiol. 1976 Oct;96(2):359–364. doi: 10.1099/00221287-96-2-359. [DOI] [PubMed] [Google Scholar]
- Hermodson M. A., Chen K. C., Buchanan T. M. Neisseria pili proteins: amino-terminal amino acid sequences and identification of an unusual amino acid. Biochemistry. 1978 Feb 7;17(3):442–445. doi: 10.1021/bi00596a010. [DOI] [PubMed] [Google Scholar]
- Johnson A. P., Taylor-Robinson D., McGee Z. A. Species specificity of attachment and damage to oviduct mucosa by Neisseria gonorrhoeae. Infect Immun. 1977 Dec;18(3):833–839. doi: 10.1128/iai.18.3.833-839.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jones R. B., Newland J. C., Olsen D. A., Buchanan T. M. Immune-enhanced phagocytosis of Neisseria gonorrhoeae by macrophages: characterization of the major antigens to which opsonins are directed. J Gen Microbiol. 1980 Dec;121(2):365–372. doi: 10.1099/00221287-121-2-365. [DOI] [PubMed] [Google Scholar]
- KELLOGG D. S., Jr, PEACOCK W. L., Jr, DEACON W. E., BROWN L., PIRKLE D. I. NEISSERIA GONORRHOEAE. I. VIRULENCE GENETICALLY LINKED TO CLONAL VARIATION. J Bacteriol. 1963 Jun;85:1274–1279. doi: 10.1128/jb.85.6.1274-1279.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kellogg D. S., Jr, Cohen I. R., Norins L. C., Schroeter A. L., Reising G. Neisseria gonorrhoeae. II. Colonial variation and pathogenicity during 35 months in vitro. J Bacteriol. 1968 Sep;96(3):596–605. doi: 10.1128/jb.96.3.596-605.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lambden P. R. Biochemical comparison of pili from variants of Neisseria gonorrhoeae P9. J Gen Microbiol. 1982 Sep;128(9):2105–2111. doi: 10.1099/00221287-128-9-2105. [DOI] [PubMed] [Google Scholar]
- Lambden P. R., Heckels J. E., James L. T., Watt P. J. Variations in surface protein composition associated with virulence properties in opacity types of Neisseria gonorrhoeae. J Gen Microbiol. 1979 Oct;114(2):305–312. doi: 10.1099/00221287-114-2-305. [DOI] [PubMed] [Google Scholar]
- Lambden P. R., Heckels J. E., Watt P. J. Effect of anti-pilus antibodies on survival of gonococci within guinea pig subcutaneous chambers. Infect Immun. 1982 Oct;38(1):27–30. doi: 10.1128/iai.38.1.27-30.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lambden P. R., Robertson J. N., Watt P. J. Biological properties of two distinct pilus types produced by isogenic variants of Neisseria gonorrhoeae P9. J Bacteriol. 1980 Jan;141(1):393–396. doi: 10.1128/jb.141.1.393-396.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lund B., Lindberg F., Normark S. Structure and antigenic properties of the tip-located P pilus proteins of uropathogenic Escherichia coli. J Bacteriol. 1988 Apr;170(4):1887–1894. doi: 10.1128/jb.170.4.1887-1894.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McChesney D., Tramont E. C., Boslego J. W., Ciak J., Sadoff J., Brinton C. C. Genital antibody response to a parenteral gonococcal pilus vaccine. Infect Immun. 1982 Jun;36(3):1006–1012. doi: 10.1128/iai.36.3.1006-1012.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Meyer T. F., Billyard E., Haas R., Storzbach S., So M. Pilus genes of Neisseria gonorrheae: chromosomal organization and DNA sequence. Proc Natl Acad Sci U S A. 1984 Oct;81(19):6110–6114. doi: 10.1073/pnas.81.19.6110. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Meyer T. F., van Putten J. P. Genetic mechanisms and biological implications of phase variation in pathogenic neisseriae. Clin Microbiol Rev. 1989 Apr;2 (Suppl):S139–S145. doi: 10.1128/cmr.2.suppl.s139. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Muir L. L., Strugnell R. A., Davies J. K. Proteins that appear to be associated with pili in Neisseria gonorrhoeae. Infect Immun. 1988 Jul;56(7):1743–1747. doi: 10.1128/iai.56.7.1743-1747.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mårdh P. A., Westtöm L. Adherence of bacterial to vaginal epithelial cells. Infect Immun. 1976 Mar;13(3):661–666. doi: 10.1128/iai.13.3.661-666.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nicolson I. J., Perry A. C., Virji M., Heckels J. E., Saunders J. R. Localization of antibody-binding sites by sequence analysis of cloned pilin genes from Neisseria gonorrhoeae. J Gen Microbiol. 1987 Apr;133(4):825–833. doi: 10.1099/00221287-133-4-825. [DOI] [PubMed] [Google Scholar]
- Olafson R. W., McCarthy P. J., Bhatti A. R., Dooley J. S., Heckels J. E., Trust T. J. Structural and antigenic analysis of meningococcal piliation. Infect Immun. 1985 May;48(2):336–342. doi: 10.1128/iai.48.2.336-342.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pearce W. A., Buchanan T. M. Attachment role of gonococcal pili. Optimum conditions and quantitation of adherence of isolated pili to human cells in vitro. J Clin Invest. 1978 Apr;61(4):931–943. doi: 10.1172/JCI109018. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Punsalang A. P., Jr, Sawyer W. D. Role of pili in the virulence of Neisseria gonorrhoeae. Infect Immun. 1973 Aug;8(2):255–263. doi: 10.1128/iai.8.2.255-263.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rest R. F., Fischer S. H., Ingham Z. Z., Jones J. F. Interactions of Neisseria gonorrhoeae with human neutrophils: effects of serum and gonococcal opacity on phagocyte killing and chemiluminescence. Infect Immun. 1982 May;36(2):737–744. doi: 10.1128/iai.36.2.737-744.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Robertson J. N., Vincent P., Ward M. E. The preparation and properties of gonococcal pili. J Gen Microbiol. 1977 Sep;102(1):169–177. doi: 10.1099/00221287-102-1-169. [DOI] [PubMed] [Google Scholar]
- Rothbard J. B., Fernandez R., Schoolnik G. K. Strain-specific and common epitopes of gonococcal pili. J Exp Med. 1984 Jul 1;160(1):208–221. doi: 10.1084/jem.160.1.208. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rothbard J. B., Fernandez R., Wang L., Teng N. N., Schoolnik G. K. Antibodies to peptides corresponding to a conserved sequence of gonococcal pilins block bacterial adhesion. Proc Natl Acad Sci U S A. 1985 Feb;82(3):915–919. doi: 10.1073/pnas.82.3.915. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Salit I. E., Blake M., Gotschlich E. C. Intra-strain heterogeneity of gonococcal pili is related to opacity colony variance. J Exp Med. 1980 Mar 1;151(3):716–725. doi: 10.1084/jem.151.3.716. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schoolnik G. K., Fernandez R., Tai J. Y., Rothbard J., Gotschlich E. C. Gonococcal pili. Primary structure and receptor binding domain. J Exp Med. 1984 May 1;159(5):1351–1370. doi: 10.1084/jem.159.5.1351. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schoolnik G. K., Tai J. Y., Gotschlich E. C. A pilus peptide vaccine for the prevention of gonorrhea. Prog Allergy. 1983;33:314–331. [PubMed] [Google Scholar]
- Seifert H. S., Ajioka R., So M. Alternative model for Neisseria gonorrhoeae pilin variation. Vaccine. 1988 Apr;6(2):107–109. doi: 10.1016/s0264-410x(88)80009-4. [DOI] [PubMed] [Google Scholar]
- Sparling P. F., Cannon J. G., So M. Phase and antigenic variation of pili and outer membrane protein II of Neisseria gonorrhoeae. J Infect Dis. 1986 Feb;153(2):196–201. doi: 10.1093/infdis/153.2.196. [DOI] [PubMed] [Google Scholar]
- Sparling P. F. Genetic transformation of Neisseria gonorrhoeae to streptomycin resistance. J Bacteriol. 1966 Nov;92(5):1364–1371. doi: 10.1128/jb.92.5.1364-1371.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stephens D. S., McGee Z. A. Attachment of Neisseria meningitidis to human mucosal surfaces: influence of pili and type of receptor cell. J Infect Dis. 1981 Apr;143(4):525–532. doi: 10.1093/infdis/143.4.525. [DOI] [PubMed] [Google Scholar]
- Stephens D. S., Whitney A. M., Rothbard J., Schoolnik G. K. Pili of Neisseria meningitidis. Analysis of structure and investigation of structural and antigenic relationships to gonococcal pili. J Exp Med. 1985 Jun 1;161(6):1539–1553. doi: 10.1084/jem.161.6.1539. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Swanson J., Barrera O. Gonococcal pilus subunit size heterogeneity correlates with transitions in colony piliation phenotype, not with changes in colony opacity. J Exp Med. 1983 Nov 1;158(5):1459–1472. doi: 10.1084/jem.158.5.1459. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Swanson J., Bergström S., Barrera O., Robbins K., Corwin D. Pilus- gonococcal variants. Evidence for multiple forms of piliation control. J Exp Med. 1985 Aug 1;162(2):729–744. doi: 10.1084/jem.162.2.729. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Swanson J., Kraus S. J., Gotschlich E. C. Studies on gonococcus infection. I. Pili and zones of adhesion: their relation to gonococcal growth patterns. J Exp Med. 1971 Oct 1;134(4):886–906. doi: 10.1084/jem.134.4.886. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Swanson J., Robbins K., Barrera O., Corwin D., Boslego J., Ciak J., Blake M., Koomey J. M. Gonococcal pilin variants in experimental gonorrhea. J Exp Med. 1987 May 1;165(5):1344–1357. doi: 10.1084/jem.165.5.1344. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Swanson J., Sparks E., Young D., King G. Studies on Gonococcus infection. X. Pili and leukocyte association factor as mediators of interactions between gonococci and eukaryotic cells in vitro. Infect Immun. 1975 Jun;11(6):1352–1361. doi: 10.1128/iai.11.6.1352-1361.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Swanson J., Sparks E., Zeligs B., Siam M. A., Parrott C. Studies on gonococcus infection. V. Observations on in vitro interactions of gonococci and human neutrophils. Infect Immun. 1974 Sep;10(3):633–644. doi: 10.1128/iai.10.3.633-644.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Swanson J. Studies on gonococcus infection. IV. Pili: their role in attachment of gonococci to tissue culture cells. J Exp Med. 1973 Mar 1;137(3):571–589. doi: 10.1084/jem.137.3.571. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Thongthai C., Sawyer W. D. Studies on the virulence of Neisseria gonorrhoeae. I. Relation of colonial morphology and resistance to phagocytosis by polymorphonuclear leukocytes. Infect Immun. 1973 Mar;7(3):373–379. doi: 10.1128/iai.7.3.373-379.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tinsley C. R., Heckels J. E. Variation in the expression of pili and outer membrane protein by Neisseria meningitidis during the course of meningococcal infection. J Gen Microbiol. 1986 Sep;132(9):2483–2490. doi: 10.1099/00221287-132-9-2483. [DOI] [PubMed] [Google Scholar]
- Tramont E. C., Ciak J., Boslego J., McChesney D. G., Brinton C. C., Zollinger W. Antigenic specificity of antibodies in vaginal secretions during infection with Neisseria gonorrhoeae. J Infect Dis. 1980 Jul;142(1):23–31. doi: 10.1093/infdis/142.1.23. [DOI] [PubMed] [Google Scholar]
- Tramont E. C. Inhibition of adherence of Neisseria gonorrhoeae by human genital secretions. J Clin Invest. 1977 Jan;59(1):117–124. doi: 10.1172/JCI108608. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tramont E. C., Sadoff J. C., Boslego J. W., Ciak J., McChesney D., Brinton C. C., Wood S., Takafuji E. Gonococcal pilus vaccine. Studies of antigenicity and inhibition of attachment. J Clin Invest. 1981 Oct;68(4):881–888. doi: 10.1172/JCI110343. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tramont E. C. Specificity of inhibition of epithelial cell adhesion of Neisseria gonorrhoeae. Infect Immun. 1976 Aug;14(2):593–595. doi: 10.1128/iai.14.2.593-595.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Trust T. J., Gillespie R. M., Bhatti A. R., White L. A. Differences in the adhesive properties of Neisseria meningitidis for human buccal epithelial cells and erythrocytes. Infect Immun. 1983 Jul;41(1):106–113. doi: 10.1128/iai.41.1.106-113.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Trust T. J., Lambden P. R., Watt P. J. The cohesive properties of variants of Neisseria gonorrhoeae strain P9: specific pilus-mediated and non-specific interactions. J Gen Microbiol. 1980 Jul;119(1):179–187. doi: 10.1099/00221287-119-1-179. [DOI] [PubMed] [Google Scholar]
- Virji M., Everson J. S., Lambden P. R. Effect of anti-pilus antisera on virulence of variants of Neisseria gonorrhoeae for cultured epithelial cells. J Gen Microbiol. 1982 May;128(5):1095–1100. doi: 10.1099/00221287-128-5-1095. [DOI] [PubMed] [Google Scholar]
- Virji M., Heckels J. E. Antigenic cross-reactivity of Neisseria pili: investigations with type- and species-specific monoclonal antibodies. J Gen Microbiol. 1983 Sep;129(9):2761–2768. doi: 10.1099/00221287-129-9-2761. [DOI] [PubMed] [Google Scholar]
- Virji M., Heckels J. E. Role of anti-pilus antibodies in host defense against gonococcal infection studied with monoclonal anti-pilus antibodies. Infect Immun. 1985 Sep;49(3):621–628. doi: 10.1128/iai.49.3.621-628.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Virji M., Heckels J. E. The effect of protein II and pili on the interaction of Neisseria gonorrhoeae with human polymorphonuclear leucocytes. J Gen Microbiol. 1986 Feb;132(2):503–512. doi: 10.1099/00221287-132-2-503. [DOI] [PubMed] [Google Scholar]
- Virji M., Heckels J. E. The role of common and type-specific pilus antigenic domains in adhesion and virulence of gonococci for human epithelial cells. J Gen Microbiol. 1984 May;130(5):1089–1095. doi: 10.1099/00221287-130-5-1089. [DOI] [PubMed] [Google Scholar]
- Virji M., Heckels J. E., Watt P. J. Monoclonal antibodies to gonococcal pili: studies on antigenic determinants on pili from variants of strain P9. J Gen Microbiol. 1983 Jun;129(6):1965–1973. doi: 10.1099/00221287-129-6-1965. [DOI] [PubMed] [Google Scholar]
- Ward M. E., Watt P. J., Robertson J. N. The human fallopian tube: a laboratory model for gonococcal infection. J Infect Dis. 1974 Jun;129(6):650–659. doi: 10.1093/infdis/129.6.650. [DOI] [PubMed] [Google Scholar]
- Zak K., Diaz J. L., Jackson D., Heckels J. E. Antigenic variation during infection with Neisseria gonorrhoeae: detection of antibodies to surface proteins in sera of patients with gonorrhea. J Infect Dis. 1984 Feb;149(2):166–174. doi: 10.1093/infdis/149.2.166. [DOI] [PubMed] [Google Scholar]