Table 1.
—Characteristics of the 983 Subjects With COPD Included in the Analysis by GOLD Stage
| Characteristic | GOLD I (n = 189) | GOLD II (n = 434) | GOLD III (n = 252) | GOLD IV (n = 108) |
| Age, y | 64 ± 10 | 63 ± 8 | 65 ± 8 | 65 ± 8 |
| Female sex, % | 38 | 47 | 48 | 42 |
| White race, % | 87 | 81 | 86 | 81 |
| BMI, kg/m2 | 27 ± 5 | 29 ± 6 | 28 ± 6 | 26 ± 6 |
| Smoking history, pack-y | 45 ± 25 | 52 ± 25 | 57 ± 29 | 57 ± 29 |
| Smoking status, % | 47 | 41 | 30 | 12 |
| Asthma history, % | 12 | 22 | 25 | 21 |
| FEV1, % predicted | 92 ± 10 | 65 ± 9 | 40 ± 6 | 23 ± 5 |
| FVC, % predicted | 109 ± 14 | 87 ± 13 | 72 ± 12 | 56 ± 13 |
| FEV1/FVC ratio | 0.64 ± 0.05 | 0.57 ± 0.08 | 0.43 ± 0.08 | 0.31 ± 0.07 |
| TLCCT, % predicted | 101 ± 16 | 96 ± 16 | 103 ± 17 | 112 ± 14 |
| Whole-lung emphysema, % | 5.4 (2.5-8.9) | 6.1 (2.6-13.7) | 16.9 (7.7-26.9) | 30.0 (19.4-40.2) |
Data are presented as mean ± SD and median (interquartile range) for continuous variables and % for binary variables. GOLD = Global Initiative for Chronic Obstructive Lung Disease; TLCCT = CT scan-based total lung capacity.