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. 1994 Sep;14(9):6117–6124. doi: 10.1128/mcb.14.9.6117

Plasmid maintenance functions encoded on Dictyostelium discoideum nuclear plasmid Ddp1.

J E Hughes 1, H Kiyosawa 1, D L Welker 1
PMCID: PMC359138  PMID: 8065344

Abstract

All of the plasmid-carried genes expressed during vegetative growth are essential for long-term maintenance of plasmid Ddp1 in the nucleus of Dictyostelium discoideum. Deletion of Ddp1 genes expressed only during development had no detectable effect on plasmid maintenance. Deletion of vegetatively expressed genes, either singly or in pairs, resulted in (i) a rapid loss of plasmid from cells grown in the absence of selection for plasmid retention, (ii) variation in the proportion of monomer to multimer forms of the plasmid molecules, and/or (iii) abnormalities in plasmid copy number. At least two plasmid-encoded gene products influence patterns of expression of plasmid genes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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