Table 2.
Relative Telomere Length and Study Cohort Clinical Characteristics in Patients with Sporadic Thyroid Cancer and Affected Members of Families with Familial Nonmedullary Thyroid Cancer
| Patient characteristics | Mean RTL±SD | p-Value |
|---|---|---|
| Sex | 0.06 | |
| Male | 0.96±0.18 | |
| Female | 1.11±0.20 | |
| Advanced T stage (T3–4) | 0.81 | |
| Yes | 1.07±0.14 | |
| No | 1.9±0.22 | |
| Lymph node metastasis | 0.82 | |
| Yes | 1.06±0.20 | |
| No | 1.07±0.16 | |
| Distant metastasis | 0.20 | |
| Yes | 0.79 | |
| No | 1.06±0.20 | |
| Extrathyroidal extension | 0.68 | |
| Yes | 1.05±0.13 | |
| No | 1.09±0.22 | |
| Lympho-vascular invasion | 0.46 | |
| Yes | 1.03±0.22 | |
| No | 1.11±0.21 | |
| Multifocality | 0.72 | |
| Yes | 1.07±0.22 | |
| No | 1.09±0.20 | |
| Disease recurrence | 0.57 | |
| Yes | 1.17±0.06 | |
| No | 1.08±0.21 | |
| Presence of benign thyroid nodules | 0.60 | |
| Yes | 1.10±0.21 | |
| No | 1.07±0.21 | |
| Thyroiditis | 0.53 | |
| Yes | 1.05±0.17 | |
| No | 1.10±0.22 | |
| History of other cancers | 0.84 | |
| Yes | 1.10±0.18 | |
| No | 1.08±0.21 | |
| Tobacco use | 0.70 | |
| Yes | 1.13±0.15 | |
| No | 1.10±0.21 | |
| Radioactive iodine treatment | 0.20 | |
| Yes | 1.05±0.20 | |
| No | 1.13±0.21 |
RTL, relative telomere length.