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. 1991 Jun;11(6):3384–3389. doi: 10.1128/mcb.11.6.3384

Cell cycle-specific expression and nuclear binding of DNA polymerase alpha.

T Stokke 1, B Erikstein 1, H Holte 1, S Funderud 1, H B Steen 1
PMCID: PMC360194  PMID: 2038340

Abstract

The expression and distribution of DNA polymerase alpha was measured by cytometry and confocal laser scanning microscopy. Expression was proportional to DNA content in proliferating cells, while only S-phase cells retained DNA polymerase alpha after detergent extraction. Nuclear DNA polymerase alpha binding may be one of the key events of S-phase entry.

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Selected References

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