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Diagnostic accuracy of methylene blue in the study groups
| Methylene Blue Retention | Histological diagnosis | Overall (PML + SCC) | |||
|---|---|---|---|---|---|
| Premalignant Lesion (PML) | Squamous Cell Carcinoma (SCC) | ||||
| Dysplasia | Hyperkeratosis without dysplasia | OSCC | No evidence of malignancy | ||
| + | 42 | 1 | 44 | 1 | |
| − | 4 | 3 | 4 | 1 | |
| Sensitivity | 91.3% | 91.6% | 91.4% | ||
| Specificity | 75% | 50% | 66.6% | ||
| Positive predictive value | 97.6% | 97.7% | 97.7% | ||
| Negative Predictive Value | 42.8% | 20% | 33.3% | ||
| Diagnostic Accuracy | 90% | 90% | 90% p < 0.0001(very significant) | ||
