Skip to main content
NIHPA Author Manuscripts logoLink to NIHPA Author Manuscripts
. Author manuscript; available in PMC: 2013 Mar 20.
Published in final edited form as: Drug Alcohol Depend. 2010 Sep 15;113(2-3):165–171. doi: 10.1016/j.drugalcdep.2010.07.021

Factors associated with attendance in 12-step groups (Alcoholics Anonymous/Narcotics Anonymous) among adults with alcohol problems living with HIV/AIDS

John Orwat 1, Jeffrey H Samet 2,3, Christopher P Tompkins 4, Debbie M Cheng 2,5, Michael P Dentato 1, Richard Saitz 2,6
PMCID: PMC3603575  NIHMSID: NIHMS235548  PMID: 20832197

Abstract

Background

Despite the value of 12-step meetings, few studies have examined factors associated with attendance among those living with HIV/AIDS, such as the impact of HIV disease severity and demographics.

Objective

This study examines predisposing characteristics, enabling resources and need on attendance at Alcoholic Anonymous (AA) and Narcotics Anonymous (NA) meetings among those living with HIV/AIDS and alcohol problems.

Methods

Secondary analysis of prospective data from the HIV-Longitudinal Interrelationships of Viruses and Ethanol study, a cohort of 400 adults living with HIV/AIDS and alcohol problems. Factors associated with AA/NA attendance were identified using the Anderson model for vulnerable populations. Generalized estimating equation logistic regression models were fit to identify factors associated with self-reported AA/NA attendance.

Results

At study entry, subjects were 75% male, 12% met diagnostic criteria for alcohol dependence, 43% had drug dependence and 56% reported attending one or more AA/NA meetings (past six months). In the adjusted model, female gender negatively associated with attendance, as were social support systems that use alcohol and/or drugs, while presence of HCV antibody, drug dependence diagnosis, and homelessness associated with higher odds of attendance.

Conclusions

Non-substance abuse related barriers to AA/NA group attendance exist for those living with HIV/AIDS, including females and social support systems that use alcohol and/or drugs. Positive associations of homelessness, HCV infection and current drug dependence were identified. These findings provide implications for policy makers and treatment professionals who wish to encourage attendance at 12-step meetings for those living with HIV/AIDS and alcohol or other substance use problems.

Keywords: HIV-infection, alcohol addiction disorder, substance-related disorders, 12 step groups, HIV/AIDS

1. Introduction

Individuals living with the Human Immunodeficiency Virus or Acquired Immune Deficiency Syndrome (HIV/AIDS) are more likely to be diagnosed with alcohol and other drug (AOD) use disorders than those individuals within the general population (Bing et al., 2001; Galvan et al., 2002; Galvan et al., 2003; Rabkin et al., 1997; Rabkin et al., 2004). The impact of AOD use by those living with HIV/AIDS presents the potential for increased challenges upon the health care delivery system (Masson et al., 2004), the heightened likelihood of risky behavior potentially resulting in new HIV infections (Palepu et al., 2003), non-adherence with antiretroviral treatments (ART) (Hendershot et al., 2009; Samet et al., 2004; Conigliaro et al, 2004; Dausey and Desai, 2003; Lucas, et al., 2002), liver complications exacerbated by co-occurring alcohol and other drug use, HIV/AIDS medications, and the hepatitis C virus (HCV) (Lucas et al., 2002; Moore et al., 2004; Palepu et al., 2003; Petry, 1999; Samet et al., 2007). While Alcoholic Anonymous (AA) and Narcotics Anonymous (NA) groups have great potential for the mental and physical health of those living with HIV/AIDS, there are few studies examining factors associated with group meeting attendance.

AA/NA meetings are the most frequently utilized recovery resource for people with AOD related problems (Narrow et al., 1993; Weisner et al., 2002; Weisner and Schmidt, 2001) and more people with drinking disorders attend AA meetings than any other recovery resource (Weisner et al., 1995; Humphreys et al., 1998). As AA/NA groups are free and widely available, they are also associated with positive outcomes, making an independent contribution to the reduction of AOD use, higher levels of abstinence and reduced levels of drinking, lower levels of incarceration, greater psychological adjustment, and lower overall treatment cost (Watson et al., 1997; Timko et al., 2000; Fiorentine and Hillhouse, 2000; Humphreys and Moos, 2001; Kaskutas et al. 2002; Kissin et al., 2003; McCrady and Share, 2003). AA/NA groups may occur in conjunction with formal systems of treatment or mandated requirements by the court system (Speiglman, 1994; Wild et al., 2002). For many, attendance is life long (Fiorentine and Hillhouse, 2000). Over the past decade, research on the process of change and outcomes associated with mutual help groups such as AA/NA supports their significance as a resource for recovery, providing guidelines for living, increasing social support networks and linkage to ongoing care (McCrady and Share, 2003).

Meta-analyses or reviews of multiple studies (Emrick et al., 1993; Tonigan et al., 1996; Bogenschultz, 2008) have reported on sociodemographic factors (e.g., spirituality, race, gender) associated with AA/NA participation. Attendance is more common among racial and ethnic minority groups, those with lower incomes, and those with unstable employment, suggesting that economic barriers may preclude formal treatment in favor of AA/NA attendance (Humphreys et al., 1998; Kaskutas et al., 1999). Prior formal substance abuse treatment is positively associated with AA/NA attendance, likely due to exposure to these groups (Humphreys et al., 1998; McCrady and Share, 2003).

Few studies of the factors associated with attendance among those living with HIV/AIDS have been published. An early paper addressed the impact of self help on HIV risk reduction, finding that in a sample of injection drug users, those who attended self help were almost twice as likely to reduce or eliminate the risk of HIV than those who did not attend (Sibthorpe, Fleming, and Gould, 1994). This study demonstrates that those attending self-help are amenable to HIV risk reduction interventions and the important role self-help can play in reducing risk. Among those living with HIV/AIDS, Burnam, et al. (2001) examined the factors associated with AA/NA attendance in the HIV Cost and Services Utilization Study (HCSUS), a national probability survey of 2,864 adults living with HIV/AIDS and receiving medical care in the United States in 1996. Controlling for need, African Americans were more likely than Whites to attend AA/NA group meetings, as were those in larger metropolitan areas and those in the Northeast, although sex, age, employment, income, and insurance were not associated with attendance. HIV clinical stage and symptom burden were not associated with attendance but lower CD4 cell count was positively associated with attendance.

This study advances previous research by examining factors associated with attendance at AA/NA group meetings among people living with HIV/AIDS in the era of antiretroviral treatments. In addition, the data set provides the opportunity to explore the impact of other factors, such as social supports, co-occurring depression, and, of particular interest, hepatitis C in a cohort with current or past alcohol problems.

2. Methods

We analyzed data collected for the HIV-Longitudinal Interrelationships of Viruses and Ethanol (HIV-LIVE) study, a prospective cohort study of 400 adults living with HIV/AIDS and alcohol problems. Eligibility criteria for this study included documentation of HIV infection, current or past alcohol problems defined as two or more positive responses to the CAGE (Cut down, Annoyed, Guilty, and Eye opener) alcohol screening questionnaire (Ewing, 1984; Samet et al., 2004) or an alcohol use disorder as assessed by a physician investigator, the ability to speak English or Spanish, a score of 21 or greater on the Mini Mental State Examination (Folstein et al., 1975; Smith et al., 2006) and plans to reside in the area for at least one year. The current analysis included subjects with two or more study interviews. All subjects provided written informed consent and were 18 years of age or older. A certificate of confidentiality was provided by NIAAA as an additional protection of subject confidentiality.

Recruitment of subjects for this study (n = 400) came from two urban hospital-based outpatient practices (30%) in Boston, MA as well as by referral of Boston Medical Center’s (BMC) practicing physicians, flyers posted in the community, medical clinics, and addiction treatment facilities (32%). Approximately 38% of participants were recruited from previous observational studies conducted by the investigators (Samet et al., 2007). After obtaining informed consent, subjects enrolled during the period August 2001 until July 2003. Baseline data were collected, and every 6 months thereafter, up to 42 months ending in March 2006. In addition to demographics, interviewers assessed current and past alcohol/drug use and problems, health care utilization, indicators of HIV disease severity, and AA/NA attendance.

2.1 Dependent Variables

The main dependent variable was at least one contact with AA/NA in the previous six months. Subjects were asked the following: “During the past 6 months, did you attend AA or NA meetings?” Secondly, subjects were asked: “How often did you generally attend?” This was followed by prompts for daily, several times a week, weekly, every two weeks, monthly, less than once a month, or other. The second dependent variable was at least weekly attendance over the previous six months, which may approximate a higher level of engagement in self help. In the absence of clear and consistent guidelines for people with substance use disorders generally, we make this approximation.

2.2 Independent variables

were selected using the Andersen Behavioral Model for Vulnerable Populations (Andersen, 1995; Weisner et al., 2002). This model is commonly used in studies to understand utilization of health care by examining three individual level domains: those factors that predispose people to utilize care (e.g., demographics), factors that enable use (e.g., ability to pay), and factors associated with need for the specific service (Andersen, 1995). The comprehensive database allowed for the exploration of other factors, which have yet to be reported on in the literature (e.g., HCV antibody status and social supports).

2.3 Predisposing variables

included age (dichotomized at the median, 44.5), sex, race (Black, White or other), marital status (married, single, or partnered but not married), sexual orientation (gay, bisexual, other vs. heterosexual), education level (high school graduate), living alone, born in the USA, sexual or physical abuse or trauma, and literacy level (a score of >60 on the Rapid Estimate of Adult Literacy in Medicine (REALM), indicating literacy at the high school level) (Davis et al., 1991). Sexual or physical abuse or trauma is considered a predisposing variable to remain consistent with previous literature (Burnam et al., 2001) and since it is not an enabling or need/severity factor when examining utilization of 12-step groups as an outcome. HIV/AIDS disease severity was assessed using CD4 cell count (dichotomized at the median), the presence of opportunistic infections or cancers, and an HIV-Symptom Index score, which is a measure of how often and how bothersome a person experiences 20 common HIV symptoms (Justice, et al., 2001; Kilbourne, et al., 2002) and the presence or absence of the hepatitis C Virus (HCV) antibody (testing was done at the first opportunity if results of testing for clinical purposes were not available).

2.4 Enabling resources

included employment status, receipt of government disability income, homelessness (spending one or more nights “on the street, without shelter” in the past 6 months), and whether or not the subject lived with children. Social support for substance abuse was assessed by asking subjects “how many of the people you spend time with” followed by three prompts “currently drink alcohol,” “are currently heavy or problem drinkers,” and “currently use drugs.” To assess social support for sobriety, subjects were asked, “How many of the people that you spend time with support your sobriety or abstinence?” The use of HIV antiretroviral medications was assessed by asking respondents if they were taking any of a list of all available specific medications over the previous six months, using photographic prompts, generic and brand names.

2.5 Need

for AA/NA variables included alcohol dependence in the past six months assessed using the Composite International Diagnostic Interview Short Form (CIDI-SF) (Kessler et al., 1998) and a diagnosis of drug dependence in the previous six months. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression scale (CES-D) (Radloff, 1977; Andresen et al., 1994) and a dichotomous variable was constructed based on a cutoff of 16 or greater. This cutoff has been shown to indicate clinically important depressive symptoms in the general population (Eaton and Kessler, 1981; Weissman et al., 1977). Involvement in the criminal justice system was measured by asking respondents if they were in jail during the previous six months.

3. Analysis

To explore the relationship between the various selected factors and AA/NA group attendance, multivariable analysis was conducted using generalized estimating equations (GEE) (Zeger and Liang, 1986; Liang and Zeger, 1986). This approach was chosen to account for correlation in the data due to incorporating repeated measures from the same subject. Models were fit using a logit link, an exchangeable working correlation structure, and the empirical variance estimator was used in all analyses. An advantage of the GEE approach is that the results are robust, i.e. valid estimates can be obtained from the empirical variance estimator even if the correlation structure is misspecified. In addition, the GEE approach is flexible and can accommodate settings where subjects have varying numbers of follow-up assessments. Independent variables were allowed to vary with time as appropriate and, to assess for potential collinearity, we verified that no pairs of independent variables were highly correlated (> 0.40). Preliminary crude analyses were performed that included only a single independent variable. A full multivariable model was then fit including all independent variables in the same model. To ensure that time varying independent variables preceded the episode of attendance, independent variables were “lagged” to predict report of AA/NA meeting attendance at the subsequent interview. If a participant missed a scheduled follow-up interview, then the outcome at the next available interview was used. We therefore also adjusted for duration of time between assessment of independent variables and outcomes. Similar analyses were used to evaluate the secondary outcome, “weekly or more frequent AA/NA attendance.” Analyses were conducted using two-sided tests and a significance level of 0.05. Due to the exploratory nature of the analyses we did not adjust for multiple comparisons. All analyses were conducted using SAS version 9.0 (SAS Institute, Inc., Cary, NC).

4. Results

4.1 Sample Characteristics

The study sample was comprised of 369 subjects who completed at least two research interviews. Of the initial 369 subjects, 91% completed three interviews, 82% (four interviews), 66% (five interviews), 63% (six interviews), 44% (seven interviews), and 6% completed an eighth interview. A majority of the sample was male, average age was 42.7 years, and was racially diverse (42.8% Black, 32.5% White, 24.7% Other) (Table 1). A majority had experienced sexual or physical abuse or trauma (80.4%), and about a third were gay, bisexual, or “some other” sexual orientation. As for HIV status, a minority had opportunitistic conditions, CD4 count averaged 462 cells/mm3 and over half had a positive hepatitis C antibody test (58%). A majority of the sample studied reported spending time with people who use alcohol and who are supportive of their sobriety (61.7%) while less than half spent time with people who use drugs (47.3%). As for need variables, 12% met the criteria for a current (past 6-month) alcohol use disorder diagnosis, while almost half met the criteria for a current (past 6-month) drug dependence diagnosis (43.1%). At study entry, 58% had attended AA or NA group meetings during the six months prior, 50% of those in the third interview had attended, 48% in the fourth, 51% in the fifth, and 43% in the sixth, 48% in the seventh, and 67% in the eighth interview.

Table 1.

Baseline Characteristics of Subjects Recruited for HIV-LIVE Study

Variable Study Sample
(n=369)
Predisposing Age, years, Mean (SD) 42.7 (7.5)
Characteristics Sex (female) 24.9%
Race (White) 32.5%
Race (Black) 42.8%
Race (Other) 24.7%
Married 6.7%
High school graduate (a) 65.0%
Lives alone 28.7%
Born in the USA 87.5%
Literacy, High school level (b) 63.7%
Gay, Bisexual, Other Sexual Orientation 32.8%
Any traumatic abuse, ever (c) 80.4%
HIV Disease Severity Variables
 Any opportunistic conditions (d) 16.6%
 HIV Quality of Life Scale, Mean (SD) (e) 9.6 (4.9)
 CD4 Count (cells/mm3), Mean (SD) 462.1 (299.4)
HCV antibody present 58.0%

Enabling Resources Employment status (unemployed) (d) 73.4%
Social support uses alcohol or drugs
 Social support drinks alcohol 61.7%
 Social support uses drugs 47.3%
Social support helps with sobriety 88.8%
Currently taking anti-HIV medications 63.7%
Received disability (d) 73.4%
Homeless (d) 24.1%

Need/Severity Alcohol Diagnosis (d), (f) 11.8%
Domain Drug dependence diagnosis (d) 43.1%
Depressive symptoms (g) 62.3%
In jail (d) 18.2%
(a)

High school graduate (12 or more years of education).

(b)

Literacy score > 60 (Davis et al., 1991).

(c)

History of sexual or physical trauma or abuse.

(d)

In the past 6 months.

(f)

Alcohol diagnosis assessed using Composite International Diagnostic Interview Short Form (CIDI-SF) (Kessler et al., 1998).

(g)

Measure of depressive symptoms where a CESD score ≥16 indicates substantial depressive symptoms.

4.2 Predictors of AA/NA Attendance

The unadjusted and full model are displayed in Table 2. In the unadjusted model (Table 2), living alone, being gay, bisexual, or a sexual orientation other than heterosexual, and alcohol or drug use by social supports had a significant negative association with attendance at AA/NA groups, while social support for sobriety, sexual or physical abuse or trauma, and homelessness in the past six months were positively associated with attendance. Need variables associated with greater odds of attendance were having a current drug dependence diagnosis, depressive symptoms, and having been in jail in the past 6 months.

Table 2.

Factors Associated with any AA/NA Meeting Attendance ¥

Crude Model Full Model

Variable Odds Ratio Adjusted Odds Ratio
(95% CI) (95% CI)
Predisposing Age (a) 1.06 (0.86, 1.32) 1 (0.97, 1.03)
Characteristics Sex (female) 0.78 (0.60, 1.01) 0.55 (0.34, 0.90) *
 Race (Black) vs. White 1.16 (0.90, 1.48) 1.36 (0.83, 2.21)
   (Other) vs. White 1.17 (0.87, 1.58) 1.01 (0.53, 1.91)
Marital Status
   Married vs. Single 0.76 (0.49, 1.19) 0.96 (0.56, 1.66)
   Partnered, not 0.90 (0.72, 1.12) 0.95 (0.73, 1.25)
married vs. Single
High school graduate (b) 0.88 (0.70, 1.10) 1.09 (0.70, 1.67)
Lives alone 0.66 (0.53, 0.83) *** 0.98 (0.75, 1.28)
Born in the USA 0.94 (0.67, 1.32) 0.82 (0.39, 1.72)
Literacy at high school level (c) 1.01 (0.80, 1.28) 1.28 (0.82, 2.00)
Gay, Bisexual, Other Sexual 0.52 (0.41, 0.66) *** 0.64 (0.40, 1.01)
Orientation vs. Heterosexual
Any traumatic abuse, ever (d) 1.40 (1.06, 1.84) * 1.66 (0.97, 2.84)
HIV Disease Severity Variables
 Any opportunistic conditions
(e)
1.04 (0.79, 1.35) 0.76 (0.56, 1.05)
 HIV Qual.of Life Scale (f) 1.47 (1.18, 1.84) *** 1.03 (0.99, 1.07)
 CD4 Count (g) 0.99 (0.79, 1.23) 1.02 (0.97, 1.08)
HCV antibody present 1.88 (1.50, 2.35) *** 2.27 (1.44, 3.58) ***

Enabling Resources Unemployed (e) 1.13 (0.88, 1.44) 0.94 (0.68, 1.31)
Social support uses alcohol or
drugs
0.47 (0.37, 0.61) *** 0.59 (0.44, 0.78) ***
Social support helps w/sobriety 2.09 (1.46, 3.00) *** 1.03 (0.73, 1.45)
Lives without children 1.25 (0.85, 1.84) 1.06 (0.70, 1.62)
Currently taking anti-HIV
medications
0.90 (0.72, 1.13) 1.03 (0.77, 1.39)
Received disability (e) 1.07 (0.81, 1.40) 0.67 (0.44, 1.01)
Homeless (e) 2.70 (2.01, 3.64) *** 1.64 (1.16, 2.33) **

Need/ Severity Alcohol Diagnosis (e), (h) 1.19 (0.85, 1.66) 0.96 (0.56, 1.66)
Drug dependence diagnosis 1.72 (1.35, 2.19) *** 1.37 (1.05, 1.79) *
Depressive symptoms (i) 1.44 (1.15, 1.79) ** 1.04 (0.80, 1.35)
In jail (e) 2.87 (1.98, 4.17) *** 1.15 (0.73, 1.80)
*

p<05

**

p<.01

***

p<.001

¥

Analyses based on 369 subjects and 1,151 observations.

a

Age is a dichotomous variable at median (44.5 years).

b

High school graduate is 12 or more years of education)

c

Literacy score > 60 (Davis et al., 1991).

d

History of sexual or physical trauma or abuse.

e

Past 6 months.

g

CD4 count a dichotomous variable at median.

h

Alcohol diagnosis using Composite International Diagnostic Interview Short Form (CIDI-SF) (Kessler et al., 1998).

i

Measure of depressive symptoms where a CESD score ≥16 indicates substantial depressive symptoms.

In the adjusted model, being female was associated with lower odds of attendance, as was a social support system that used alcohol and/or drugs. The presence of HCV antibody and homelessness in the previous 6 months were associated with higher odds of attendance at an AA/NA group, as was having a drug dependence diagnosis.

When the dependent variable was defined as AA/NA attendance weekly or more often (Table 3), few differences emerged in the multivariable model except for minor changes in magnitude and significance of odds ratios. Being female and social supports using alcohol or drugs were still associated with lower odds of AA/NA attendance, while the presence of hepatitis C antibody and meeting the criteria for drug dependence were associated with an increased odds. The association between homelessness and AA/NA attendance was attenuated and no longer statistically significant.

Table 3.

Factors Associated with AA/NA Attendance Weekly or More Often ¥

Variable Adjusted Odds Ratio
(95% CI)
Predisposing Age (a) 1.01 (0.98, 1.04)
Characteristics Sex (female) 0.53 (0.32, 0.89) *
Race (Black) vs. White 1.21 (0.74, 1.96)
   (Other) vs. White 0.95 (0.52, 1.75)
Marital Status (Married vs. Single) 0.60 (0.30, 1.19)
   (Partnered, not married vs. 0.88 (0.67, 1.17)
Single)
High school graduate (b) 0.80 (0.52, 1.23)
Lives alone 0.93 (0.69, 1.25)
Born in the USA 0.85 (0.42, 1.71)
Literacy, High school level (c) 1.35 (0.86, 2.12)
Gay, Bisexual, Other Sexual 0.80 (0.51, 1.27)
Orientation vs. Heterosexual
Any traumatic abuse, ever (d) 1.26 (0.74, 2.14)
HIV DISEASE SEVERITY
VARIABLES
 Any opportunistic conditions (e) 0.75 (0.55, 1.02)
 HIV Quality of Life Scale (f) 1.01 (0.98, 1.04)
 CD4 Count (g) 0.99 (0.94, 1.05)
HCV antibody present 2.05 (1.31, 3.20) **

Enabling Resources Unemployed (e) 0.80 (0.58, 1.09)
 Social support uses alcohol or drugs 0.56 (0.42, 0.74) ***
 Social support helps with sobriety 1.03 (0.71, 1.50)
Lives without children 1.22 (0.70, 2.11)
Currently taking anti-HIV medications 1.03 (0.75, 1.41)
Received disability (e) 0.73 (0.47, 1.13)
Homeless (e) 1.33 (0.94, 1.87)

Need/Severity Alcohol Diagnosis (e), (h) 0.99 (0.57, 1.75)
Drug dependence diagnosis 1.63 (1.22, 2.18) **
Depressive symptoms (i) 0.94 (0.71, 1.24)
In jail (e) 1.48 (0.94, 2.35)
*

p<.05

**

p<.01

***

p<.001

¥

Analyses based on 369 subjects and 1,151 observations.

(a)

Age is a dichotomous variable at median (44.5 years).

(b)

High school graduate (12 or more years of education).

(c)

Literacy score > 60 (Davis et al., 1991).

(d)

History of sexual or physical trauma or abuse.

(e)

Past 6 months.

(g)

CD4 count is a dichotomous variable at median.

(h)

Alcohol diagnosis using Composite International Diagnostic Interview Short Form (CIDI-SF) (Kessler et al., 1998).

(i)

Measure of depressive symptoms where a CESD score ≥16 indicates substantial depressive symptoms.

5. Discussion

AA/NA group attendance by those living with HIV/AIDS and alcohol problems is impacted by a variety of factors. Factors that facilitate AA/NA group meeting attendance include a drug dependence diagnosis, homelessness, and the presence of HCV antibody. The odds of attendance were lower for subjects who were female or had social supports that use alcohol or other drugs. When AA/NA was defined as weekly or more frequent attendance, results were similar except the effect of homelessness was no longer statistically significant.

This study underscores the unique differences with regard to attendance in AA/NA groups by those living with HIV/AIDS. While Burnam et al., (2001) did not find significance for demographics including certain geographic locations, sex, age, employment, income, and insurance status, this study revealed the relevance of gender, social supports, homelessness, a drug dependence diagnosis and presence of the HCV antibody with regard to a greater likelihood of attendance or non-attendance of AA/NA groups.

Female gender was negatively associated with attendance in AA/NA, and the negative association between gender and AA/NA group attendance found in this study is not necessarily congruent with much of the literature. Some population studies show that women are more likely to drop out of AA/NA (Humphreys et al., 1994) and may not participate for reasons related to program structure, challenges related to lack childcare or if they sense AA/NA is punitive and male dominated (Kaskutas, 1994). Other studies demonstrate that while women may drop out of 12 step attendance more than men after 12 months of treatment (Humphreys et al., 1991), they were more likely to attend in the first place (Humphreys et al., 1994). However, in those studies, after the initial dropout period, women were found to attend as regularly as men (Humphreys et al., 1994). Additionally gender and other sociodemographic variables have not been reliably found to be strongly associated with 12-step attendance in prior studies among general groups of substance abusers (Bogenschultz, 2008; Emrick et al., 1993; Tonigan et al., 1996) or among HIV+ substance users (Burnam et al., 2001).

Social supports currently using alcohol or other drugs were negatively associated with AA/NA group attendance. These findings are consistent with general population studies (Hasin and Grant, 1995; Kaskutas et al., 2002; Witbrodt and Kaskutas, 2005; Moos and Moos, 2006; Kaskutas et al., 2009) related to the negative impact of social supports using alcohol and other drugs on the attendance of those attending AA/NA. This study affirms the negative impact of social supports using alcohol and other drugs on those living with HIV/AIDS who likely would attend AA/NA groups.

There is also a strong and positive independent association with co-occurring hepatitis C, which may be the result of a multi-faceted approach to treatment that coordinates efforts and systematically integrates care. Attendance may also be motivated in an effort to abstain from alcohol or other drugs as it may further complicate their existing health conditions such as hepatitis C. The increased likelihood of AA/NA group attendance among those with co-occurring hepatitis C has implications for clinical practice and policy and is important that both medical and addiction treatment staff clearly understand HIV disease progression and a co-occurring diagnosis of hepatitis C.

On the system level, it would be useful to research the specific mechanisms that facilitate greater attendance of AA/NA groups. The strong and positive association of homelessness and attendance at AA/NA groups, may be due to placement of homeless individuals using substances into detoxification programs or residential services with programmatic requirements as a condition of entry or continuation in the shelters (Kertesz, et al., 2006). Such implications may include exploration of expansion of social networks for the homeless or holding AA/NA groups at convenient locations such as a shelter. Homeless and other low-income persons may be more likely than middle or high income persons to participate in cost-free services for several reasons (e.g., lack of access to other services).

There was also a positive association of those with a drug dependence diagnosis and increased attendance of AA/NA groups while findings were not as significant for those with an alcohol diagnosis or depressive symptoms. This finding, while consistent with other studies (Kaskutas et al., 2009) is curious, and may be related to the fact in addition to seeking specific care such as pharmacotherapy or detoxification, that those with a drug dependence diagnosis are more likely to seek attendance and maintain additional support during and after treatment through AA/NA groups (Timko et al., 2006).

This study offers insight with regard to the factors that may lead to AA/NA group attendance among those living with HIV/AIDS, particularly complementing the literature for those with long-term alcohol and substance use disorders. An additional strength of this study is that the data are quite detailed, which allows for the further examination of the negative impact of social supports that use alcohol or drugs, the role of gender, homelessness, a drug dependence diagnosis, and co-occurring hepatitis C status on AA/NA group attendance. However, limitations of the study are also worth noting. First, the analysis could be strengthened by considering contextual and ecological factors that play a role in participation in AA/NA for those living with HIV/AID, such as the availability of meetings as well as the degree to which the values of the individual are congruent with those manifest in the meetings (Mankowski, Humphreys, & Moos, 2001). Such variables, however, were not available in our data so these analyses were not performed. Second, generalizability of results is limited since data used for this study were collected on people living with HIV/AIDS and alcohol problems in the Boston area. The findings are likely applicable to people with HIV/AIDS in similar urban locations. In addition, the observed associations while informative may not be causal.

Reliance on self-reported data is another limitation of this study, which may lead to measurement bias, in that subjects may not accurately report specific behaviors or AA/NA group attendance. Studies do show that self-report is consistent when respondents are asked about service utilization, but may be less reliable when assessing quantity of services (Goldberg et al., 2002). Bias in self-report may have been attenuated in this study by use of validated interview questions as well as the minimization of contextual factors that may influence the possibility of biased self report (Del Boca and Darkes, 2003), along with trained research assistants who emphasized confidentiality and took a systematic approach to interviewing, and a certificate of confidentiality provided by NIAAA as an additional protection of subject privacy.

Despite these limitations, this study offers valuable insight into the factors leading to attendance of AA/NA groups among a cohort of people living with HIV/AIDS. Results have relevance for administrators, clinicians and direct service providers working within the realms of HIV/AIDS, alcohol and other drug treatment, and AA/NA groups. Few data are available about this hard to reach population and AA/NA group attendance. This study has examined these questions using a rich data set that includes detailed predisposing, enabling, and need variables and has made use of clinical data.

This study examined the individual level factors associated with AA/NA group attendance among a cohort of adults living with HIV/AIDS. Of particular interest are variables that are barriers to AA/NA group attendance, such as gender and social supports’ use alcohol and drugs. A strong positive association of other variables, such as a drug dependence diagnosis, co-occurring hepatitis C and homelessness indicates the possibility that current policies and practices by medical professionals or amongst service providers are encouraging AA/NA group attendance. Alternatively, the medical challenge of a hepatitis C diagnosis may be a motivator to seek care in the form of AA/NA for one’s addiction. Understanding the factors that facilitate or impede AA/NA group attendance may improve the development of strategies to increase attendance, service delivery, referral and care, which is of critical importance for most vulnerable populations.

More research concerning barriers for women and AA/NA attendance is worthwhile since AA/NA is valuable for women in maintaining their sobriety (Beckman, 1993) for many of the same reasons men find AA/NA useful, such as fellowship, group support, and guidance (Kaskutas, 1994). Strategies to increase attendance of women in self help programs may include: increased referrals by medical practitioners to specialty treatment, self help programmatic support to meet the needs of subgroups of women who may have child care challenges or would benefit from meetings for women only, encouragement of female mentorship and/or sponsorship early in the self help process, while paying particular attention to other forms of self-help in the community that may assist in maintaining sobriety. This important issue warrants further exploration, especially in light of the increasing prevalence of HIV/AIDS among ethnic and racial minorities, and most notably women (Orwat, 2004).

There are several potential solutions to increase access and attendance among the specific populations identified with AA/NA groups. Much of this will certainly depend upon the role of medical, mental health and addiction professionals’ successful ability to assess needs and link individuals into the appropriate group. However, additional factors must be considered with regard to the elimination of barriers, such as how to work with individuals that have social supports that are using alcohol or other drugs and creating barriers to access and attendance of supportive services such as AA/NA groups.

Footnotes

Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

References

  1. Andersen RM. Revisiting the behavioral-model and access to medical care - Does it matter. J Health Soc Behav. 1995;36(1):1–10. [PubMed] [Google Scholar]
  2. Andresen EM, Malmgren JA, Carter WB, Patrick DL. Screening for depression in well older adults-Evaluation of a short-form of the CES-D. Am J Prev Med. 1994;10:77–84. [PubMed] [Google Scholar]
  3. Beckman LJ. Alcoholics Anonymous and gender issues. In: McCrady BS, Miller WR, editors. Research on Alcoholics Anonymous: Opportunities and Alternatives. Rutgers Center of Alcohol Studies; New Brunswick, NY: 1993. [Google Scholar]
  4. Bing EG, Burnam A, Longshore D, Fleishman JA, Sherbourne CD, London AS, Turner BJ, Eggan F, Beckman R, Vitiello B, Morton SC, Orlando M, Bozzette SA, Ortiz-Barron L, Shapiro M. Psychiatric disorders and drug use among human immunodeficiency virus-infected adults in the United States. Arch Gen Psychiatry. 2001;58(8):721–728. doi: 10.1001/archpsyc.58.8.721. [DOI] [PubMed] [Google Scholar]
  5. Bogenschutz M. Individual and contextual factors that influence AA affiliation and outcomes. In: Galanter M, Kaskutas L, editors. Recent Developments in Alcoholism: Vol. 18, Research on Alcoholics Anonymous and spirituality in addiction recovery. Springer; Totowa, NJ: 2008. pp. 413–428. [DOI] [PubMed] [Google Scholar]
  6. Burnam MA, Bing EG, Morton SC, Sherbourne C, Fleishman JA, London AS, Vitiello B, Stein M, Bozzette SA, Shapiro MF. Use of mental health and substance abuse treatment services among adults with HIV in the United States. Arch Gen Psychiatry. 2001;58(8):729–736. doi: 10.1001/archpsyc.58.8.729. [DOI] [PubMed] [Google Scholar]
  7. Conigliaro J, Madenwald T, Bryant K, Braithwaite S, Gordon A, Fultz SL, Maisto S, Samet J, Kraemer K, Cook R, Day N, Roach D, Richey S, Justice A. The veterans aging cohort study: Observational studies of alcohol use, abuse, and outcomes among human immunodeficiency virus-infected veterans. Alcohol Clin Exp Res. 2004;28(2):313–321. doi: 10.1097/01.alc.0000113414.73220.21. [DOI] [PubMed] [Google Scholar]
  8. Dausey DJ, Desai RA. Psychiatric comorbidity and the prevalence of HIV infection in a sample of patients in treatment for substance abuse. J Nerv Ment Dis. 2003;191(1):10–17. doi: 10.1097/00005053-200301000-00003. [DOI] [PubMed] [Google Scholar]
  9. Davis TC, Crouch MA, Long SW, Jackson RH, Bates P, George RB, Bairnsfather LE. Rapid assessment of literacy levels of adult primary care patients. Fam Med. 1991;23(6):433–435. [PubMed] [Google Scholar]
  10. Del Boca FK, Darkes J. The validity of self-reports of alcohol consumption: State of the science and challenges for research. Addiction. 2003;98:1–12. doi: 10.1046/j.1359-6357.2003.00586.x. [DOI] [PubMed] [Google Scholar]
  11. Eaton WW, Kessler LG. Rates of Symptoms of Depression in a National Sample. Am J Epidemiol. 1981;114(4):528–538. doi: 10.1093/oxfordjournals.aje.a113218. [DOI] [PubMed] [Google Scholar]
  12. Emrick C, Tonigan J, Montgomery H, Little L. Research on Alcoholics Anonymous: What is currently known. In: McCrady B, Miller W, editors. Research on Alcoholics Anonymous: Opportunities and alternatives. Rutgers Press; New Brunswick, NJ: 1993. pp. 41–78. [Google Scholar]
  13. Ewing JA. Detecting Alcoholism - the Cage Questionnaire. JAMA. 1984;252(14):1905–1907. doi: 10.1001/jama.252.14.1905. [DOI] [PubMed] [Google Scholar]
  14. Fiorentine R, Hillhouse MP. Drug treatment and 12-step program participation - The additive effects of integrated recovery activities. J Subst Abuse Treat. 2000;18(1):65–74. doi: 10.1016/s0740-5472(99)00020-3. [DOI] [PubMed] [Google Scholar]
  15. Folstein MF, Folstein SE, McHugh PR. Mini-mental state: A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189–198. doi: 10.1016/0022-3956(75)90026-6. [DOI] [PubMed] [Google Scholar]
  16. Galvan FH, Bing EG, Fleishman JA, London AS, Caetano R, Burnam MA, Longshore D, Morton SC, Orlando M, Shapiro M. The prevalence of alcohol consumption and heavy drinking among people with HIV in the United States: Results from the HIV cost and services utilization study. J Stud Alcohol. 2002;63(2):179–186. doi: 10.15288/jsa.2002.63.179. [DOI] [PubMed] [Google Scholar]
  17. Galvan FH, Burnam MA, Bing EG. Co-occurring psychiatric symptoms and drug dependence or heavy drinking among HIV-positive people. J Psychoactive Drugs. 2003:153–160. doi: 10.1080/02791072.2003.10400510. [DOI] [PubMed] [Google Scholar]
  18. Goldberg RW, Seybolt DC, Lehman A. Reliable self-report of health service use by individuals with serious mental illness. Psychiatr Serv. 2002;53(7):879–881. doi: 10.1176/appi.ps.53.7.879. [DOI] [PubMed] [Google Scholar]
  19. Hasin DS, Grant BF. AA and other helpseeking for alcohol problems: Former drinkers in the U.S. general population. J Subst Abuse. 1995;7(3):281–292. doi: 10.1016/0899-3289(95)90022-5. [DOI] [PubMed] [Google Scholar]
  20. Hendershot CS, Stoner SA, Pantalone DW, Simoni JM. Alcohol use and antiretroviral adherence: Review and meta-analysis. J Acquir Immune Defic Syndr. 2009:1–23. doi: 10.1097/QAI.0b013e3181b18b6e. (Epub ahead of print) [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Humphreys K, Finney JW, Moos RH. Applying a Stress and Coping Framework to Research on Mutual Help Organizations. J Community Psychol. 1994;22(4):312–327. [Google Scholar]
  22. Humphreys K, Kaskutas LA, Weisner C. The relationship of pre-treatment Alcoholics Anonymous affiliation with problem severity, social resources and treatment history. Drug Alcohol Depend. 1998;49(2):123–131. doi: 10.1016/s0376-8716(97)00155-5. [DOI] [PubMed] [Google Scholar]
  23. Humphreys K, Mavis BE, Stöffelmayr BE. Factors predicting attendance at self-help groups after substance abuse treatment: Preliminary findings. Journal of Consulting and Clinical Psychology. 1991;59:591–593. doi: 10.1037//0022-006x.59.4.591. [DOI] [PubMed] [Google Scholar]
  24. Humphreys K, Mavis BE, Stöffelmayr BE. Are twelve step programs appropriate for disenfranchised groups?: Evidence from a study of posttreatment mutual help group involvement. Prevention in Human Services. 1994;11:165–180. [Google Scholar]
  25. Humphreys K, Moos R. Can encouraging substance abuse patients to participate in self-help groups reduce demand for health care? A quasi-experimental study. Alcohol Clin Exp Res. 2001;25(5):711–716. [PubMed] [Google Scholar]
  26. Justice AC, Homes W, Gifford AL, Rabeneck L, Zackin R, Sinclair G, Weissman S, Neidig J, Marcus C, Chesney M, Cohn SE, Wu AW, Adult AIDS Clinical Trials Unit Outcomes Committee Development and validation of a self completed symptom index. J Clin Epidemiol. 2001;54(1):77–90. doi: 10.1016/s0895-4356(01)00449-8. [DOI] [PubMed] [Google Scholar]
  27. Kaskutas LA. What do women get out of self-help - Their reasons for attending women for sobriety and Alcoholics-Anonymous. J Subst Abuse Treat. 1994;11(3):185–195. doi: 10.1016/0740-5472(94)90075-2. [DOI] [PubMed] [Google Scholar]
  28. Kaskutas LA, Keller JW, Witbrodt J. Measuring social model in California: How much has changed? Contemp Drug Probl. 1999;26:607–631. [Google Scholar]
  29. Kaskutas LA, Bond J, Humphreys K. Social networks as mediators of the effect of Alcoholics Anonymous. Addiction. 2002;97(7):891–900. doi: 10.1046/j.1360-0443.2002.00118.x. [DOI] [PubMed] [Google Scholar]
  30. Kaskutas LA, Subbaraman MS, Witbrodt J, Zenmore SE. Effectiveness of making alcoholics anonymous easier: A group format 12-step facilitation approach. J Subst Abuse Treat. 2009;37:228–239. doi: 10.1016/j.jsat.2009.01.004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Kertesz SG, Larson MJ, Cheng DM, Tucker JA, Winter M, Mullins A, Saitz R, Samet JH. Need and non-need factors associated with addiction treatment utilization in a cohort of homeless and housed urban poor. Med Care. 2006;44(3):225–233. doi: 10.1097/01.mlr.0000199649.19464.8f. [DOI] [PubMed] [Google Scholar]
  32. Kessler R, Andrews G, Mroczeek D, Ustun B, Wittchen H. The World Health Organization Composite International Diagnostic Interview Short-Form (CIDI-SF) Int J Methods Psychiatr Res. 1998;7:171–185. [Google Scholar]
  33. Kilbourne AM, Justice AC, Rollman BL, McGinnis KA, Rabeneck L, Weissman S, Smola S, Schultz R, Whittle J, Rodriques-Barradas M. Clinical importance of HIV and depressive symptoms among veterans with HIV infection. J Gen Intern Med. 2002;17(7):512–520. doi: 10.1046/j.1525-1497.2002.10803.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Kissin W, McLeod C, McKay J. The longitudinal relationship between self-help group attendance and course of recovery. Eval Program Plann. 2003;26(3):311–323. [Google Scholar]
  35. Liang KY, Zeger SL. Longitudinal Data-Analysis Using Generalized Linear-Models. Biometrika. 1986;73(1):13–22. [Google Scholar]
  36. Lucas GM, Gebo KA, Chaisson RE, Moore RD. Longitudinal assessment of the effects of drug and alcohol abuse on HIV-1 treatment outcomes in an urban clinic. AIDS. 2002;16(5):767–774. doi: 10.1097/00002030-200203290-00012. [DOI] [PubMed] [Google Scholar]
  37. Mankowski ES, Humphreys K, Roos RH. Individual and contextual predictors of involvement in twelve-step self-help groups after substance abuse treatment. American Journal of Community Psychology. 2001;29(4):537–563. doi: 10.1023/A:1010469900892. [DOI] [PubMed] [Google Scholar]
  38. Masson CL, Sorensen JL, Phibbs CS, Okin RL. Predictors of medical service utilization among individuals with co-occurring HIV infection and substance abuse disorders. AIDS Care. 2004;16(6):744–755. doi: 10.1080/09540120412331269585. [DOI] [PubMed] [Google Scholar]
  39. McGrady BS, Share D. Recent research into twelve step programs. In: Graham AW, Shultz TK, Mayo-Smith MF, Ries RK, Wilford BB, editors. Principles of addiction medicine. American Society of Addiction Medicine; MD: 2003. pp. 955–968. [Google Scholar]
  40. Moore RD, Keruly JC, Chaisson RE. Differences in HIV disease progression by injecting drug use in HIV-infected persons in care. J Acquir Immune Defic Syndr. 2004;35(1):46–51. doi: 10.1097/00126334-200401010-00006. [DOI] [PubMed] [Google Scholar]
  41. Moos RH, Moos BS. Participation in treatment and Alcoholics Anonymous: A 16-year follow-up of initially untreated individuals. J Clin Psychol. 2006;62(6):735–750. doi: 10.1002/jclp.20259. [DOI] [PMC free article] [PubMed] [Google Scholar]
  42. Narrow WE, Regier DA, Rae DS, Manderscheid RW, Locke BZ. Use of services by persons with mental and addictive disorders - Findings from the National Institute of Mental Health epidemiologic catchment area program. Arch Gen Psychiatry. 1993;50(2):95–107. doi: 10.1001/archpsyc.1993.01820140017002. [DOI] [PubMed] [Google Scholar]
  43. Nelder JA, Wedderburn WM. Generalized Linear Models. J R Stat Soc Ser A. 1972;135(3):370. [Google Scholar]
  44. Orwat J. HIV/AIDS in Massachusetts: A decade of change and challenge. Massachusetts Health Policy Forum; Boston: 2004. [Google Scholar]
  45. Palepu A, Tyndall M, Yip B, O’Shaughnessy MV, Hogg RS, Montaner JSG. Impaired virologic response to highly active antiretroviral therapy associated with ongoing injection drug use. J Acquir Immune Defic Syndr. 2003;32(5):522–526. doi: 10.1097/00126334-200304150-00009. [DOI] [PubMed] [Google Scholar]
  46. Petry NM. Alcohol use in HIV patients: What we don’t know may hurt us. Int J STD AIDS. 1999;10(9):561–570. doi: 10.1258/0956462991914654. [DOI] [PubMed] [Google Scholar]
  47. Rabkin JG, Ferrando SJ, Jacobsberg LB, Fishman B. Prevalence of Axis I disorders in an AIDS cohort: A cross-sectional, controlled study. Compr Psychiatry. 1997;38(3):146–164. doi: 10.1016/s0010-440x(97)90067-5. [DOI] [PubMed] [Google Scholar]
  48. Rabkin JG, McElhiney MC, Ferrando SJ. Mood and substance use disorders in older adults with HIV/AIDS: Methodological issues and preliminary evidence. AIDS. 2004;18:S43–S48. [PubMed] [Google Scholar]
  49. Radloff L. The CES-D Scale: A self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1:385–401. [Google Scholar]
  50. Samet JH, Cheng DM, Libman H, Nunes DP, Alperen JK, Saitz R. Alcohol consumption and HIV disease progression. J Acquir Immune Defic Syndr. 2007;46(2):194–199. doi: 10.1097/QAI.0b013e318142aabb. [DOI] [PMC free article] [PubMed] [Google Scholar]
  51. Samet JH, Horton NJ, Meli S, Freedberg KA, Palepu A. Alcohol consumption and antiretroviral adherence among HIV-infected persons with alcohol problems. Alcohol Clin Exp Res. 2004;28(4):572–577. doi: 10.1097/01.alc.0000122103.74491.78. [DOI] [PubMed] [Google Scholar]
  52. Samet JH, Phillips SJ, Horton NJ, Traphagen ET, Freedberg KA. Detecting alcohol problems in HIV-infected patients: Use of the CAGE questionnaire. AIDS Res Hum Retroviruses. 2004;20(2):151–155. doi: 10.1089/088922204773004860. [DOI] [PubMed] [Google Scholar]
  53. Sibthorpe B, Fleming D, Gould J. Self-help groups: a key to HIV risk reduction for high risk drug users? Journal of AIDS. 1994;7(6):592–598. [PubMed] [Google Scholar]
  54. Smith KL, Horton NJ, Saitz R, Samet JH. The use of mini-mental state examination in recruitment for substance abuse research studies. Drug Alcohol Depend. 2006;82(3):231–237. doi: 10.1016/j.drugalcdep.2005.09.012. [DOI] [PubMed] [Google Scholar]
  55. Speiglman R. Mandated AA Attendance for Recidivist Drinking Drivers - Ideology, Organization, and California Criminal-Justice Practices. Addiction. 1994;89(7):859–868. doi: 10.1111/j.1360-0443.1994.tb00989.x. [DOI] [PubMed] [Google Scholar]
  56. Timko C, Moos RH, Finney JW, Lesar MD. Long-term outcomes of alcohol use disorders: Comparing untreated individuals with those in alcoholics anonymous and formal treatment. J Stud Alcohol. 2000;61(4):529–540. doi: 10.15288/jsa.2000.61.529. [DOI] [PubMed] [Google Scholar]
  57. Timko C, DeBenedetti A, Billow R. Intensive referral to 12-step self-help groups and 6-month substance use disorder outcomes. Addiction. 2006;101:678–688. doi: 10.1111/j.1360-0443.2006.01391.x. [DOI] [PubMed] [Google Scholar]
  58. Tonigan J, Toscova R, Miller W. Meta-analysis of the Alcoholics Anonymous literature: Sample and study characteristics moderate findings. Journal of Studies on Alcohol. 1996;57:65–72. doi: 10.15288/jsa.1996.57.65. [DOI] [PubMed] [Google Scholar]
  59. Watson CG, Hancock M, Gearhart LP, Mendez CM, Malovrh P, Raden M. A comparative outcome study of frequent, moderate, occasional, and nonattenders of alcoholics anonymous. J Clin Psychol. 1997;53(3):209–214. doi: 10.1002/(sici)1097-4679(199704)53:3<209::aid-jclp3>3.0.co;2-m. [DOI] [PubMed] [Google Scholar]
  60. Weisner C, Greenfield T, Room R. Trends in the Treatment of Alcohol-Problems in the U.S. General-Population, 1979 through 1990. Am J Public Health. 1995;85(1):55–60. doi: 10.2105/ajph.85.1.55. [DOI] [PMC free article] [PubMed] [Google Scholar]
  61. Weisner C, Matzger H, Tam T, Schmidt L. Who goes to alcohol and drug treatment? Understanding utilization within the context of insurance. J Stud Alcohol. 2002;63(6):673–682. doi: 10.15288/jsa.2002.63.673. [DOI] [PubMed] [Google Scholar]
  62. Weisner C, Schmidt LA. Rethinking access to alcohol treatment. In: Galanter M, editor. Recent Developments in Alcoholism. Vol. 15. Kluwer Academic/Plenum Publishers; New York: 2001. pp. 107–136. [DOI] [PubMed] [Google Scholar]
  63. Weissman MM, Sholomskas D, Pottenger M, Prusoff BA, Locke BZ. Assessing Depressive Symptoms in 5 Psychiatric Populations Validation Study. Am J Epidemiol. 1977;106(3):203–214. doi: 10.1093/oxfordjournals.aje.a112455. [DOI] [PubMed] [Google Scholar]
  64. Wild TC, Roberts AB, Cooper EL. Compulsory substance abuse treatment: An overview of recent findings and issues. Eur Addict Res. 2002;8(2):84–93. doi: 10.1159/000052059. [DOI] [PubMed] [Google Scholar]
  65. Witbrodt J, Kaskutas LA. Does diagnosis matter? Differential effects of 12-step participation and social networks. Am J Drug Alcohol Abuse. 2005;31:685–707. doi: 10.1081/ada-68486. [DOI] [PubMed] [Google Scholar]
  66. Zeger SL, Liang KY. Longitudinal Data-Analysis for Discrete and Continuous Outcomes. Biometrics. 1986;42(1):121–130. [PubMed] [Google Scholar]

RESOURCES