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. 1992 Nov;12(11):5217–5227. doi: 10.1128/mcb.12.11.5217

Characterization of a new tissue-specific transcription factor binding to the simian virus 40 enhancer TC-II (NF-kappa B) element.

A L Lattion 1, E Espel 1, P Reichenbach 1, C Fromental 1, P Bucher 1, A Israël 1, P Baeuerle 1, N R Rice 1, M Nabholz 1
PMCID: PMC360455  PMID: 1328873

Abstract

We have biochemically and functionally characterized a new transcription factor, NP-TCII, which is present in nuclei from unstimulated T and B lymphocytes but is not found in nonhematopoietic cells. This factor has a DNA-binding specificity similar to that of NF-kappa B but is unrelated to this or other Rel proteins by functional and biochemical criteria. It can also be distinguished from other previously described lymphocyte-specific DNA-binding proteins.

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Selected References

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