Table 1.
HIV-1 DNA integration sites and host-virus junction sequence
| Seq ID | Inhibitor | Chr | Locus | Strand | RefSeq gene | Insertion | Deletion |
|---|---|---|---|---|---|---|---|
| 100902 |
DMSO |
20 |
33371451 |
plus |
NCOA6 |
- |
- |
| 100903 |
DMSO |
17 |
35993714 |
minus |
DDX52 |
- |
- |
| 100904 |
DMSO |
3 |
156651874 |
minus |
LEKR1 |
- |
- |
| 100906 |
DMSO |
20 |
60900963 |
minus |
LAMA5 |
- |
- |
| 100907 |
DMSO |
3 |
19680267 |
minus |
DLG1 |
- |
- |
| 100910 |
DMSO |
4 |
150767744 |
plus |
- |
- |
- |
| 100912 |
DMSO |
9 |
131400460 |
plus |
WDR34 |
- |
- |
| 100914 |
DMSO |
1 |
156020423 |
minus |
UBQLN4 |
11bp (ACAGCAGTTAG) |
37 bp |
| 100916 |
DMSO |
17 |
43551920 |
minus |
PLEKHM1 |
- |
- |
| 100919 |
DMSO |
20 |
2467413 |
minus |
ZNF343 |
- |
- |
| 100921 |
DMSO |
10 |
114725221 |
minus |
TCF7L2 |
- |
- |
| 106501 |
DMSO |
4 |
87017147 |
plus |
MAPK10 |
- |
- |
| 106502 |
DMSO |
2 |
98458616 |
minus |
TMEM131 |
- |
- |
| 106505 |
DMSO |
15 |
44399565 |
minus |
FRMD10 |
- |
- |
| 106506 |
DMSO |
2 |
197544261 |
plus |
CCDC150 |
- |
- |
| 106510 |
DMSO |
7 |
333212296 |
minus |
BBS9 |
- |
- |
| 106513 |
DMSO |
2 |
230499770 |
plus |
DNER |
- |
- |
| 106520 |
DMSO |
17 |
38682989 |
plus |
CR597260 |
- |
- |
| 106521 |
DMSO |
19 |
17213409 |
minus |
MY09B |
- |
- |
| 106524 |
DMSO |
6 |
33219360 |
plus |
VPS52 |
- |
- |
| 100925 |
RAL |
9 |
33033919 |
plus |
DNAJA1 |
- |
9 bp |
| 100931 |
RAL |
14 |
44024820 |
minus |
- |
- |
20 bp |
| 100937 |
RAL |
2 |
102387409 |
plus |
MAP4K4 |
9 bp (GACACTTAG0 |
- |
| 100940 |
RAL |
5 |
176735496 |
plus |
MXD3 |
2 bp (AC) |
- |
| 100944 |
RAL |
3 |
105267040 |
plus |
- |
21 bp (AATAAAAAGGTACAAATAGAC) |
- |
| 106525 |
RAL |
14 |
87606685 |
minus |
- |
6 bp (TCATAA) |
3 bp |
| 106530 |
RAL |
22 |
36006496 |
plus |
MB |
1 bp (A) |
9 bp |
| 106534 |
RAL |
7 |
130544996 |
minus |
CR618431 |
10 bp (TTGTAATTAC) |
- |
| 106537 |
RAL |
1 |
63779999 |
minus |
BC040309 |
16 bp (AAAGAAAAGGGGGGAC) |
- |
| 106538 |
RAL |
3 |
190624485 |
minus |
- |
- |
4 bp |
| 106540 |
RAL |
3 |
85084717 |
minus |
CADM2 |
- |
- |
| 106542 |
RAL |
18 |
40381428 |
minus |
RIT2 |
2 bp (CA) |
1 bp |
| 106558 |
RAL |
6 |
52427867 |
minus |
TRAM2 |
- |
- |
| 106574 |
RAL |
9 |
18460635 |
plus |
- |
9 bp (ACACCTAAT) |
- |
| 106582 |
RAL |
1 |
6482403 |
minus |
HES2 |
4 bp (GGAC) |
- |
| 106588 |
RAL |
11 |
28954901 |
plus |
- |
4 bp (GGAC) |
- |
| 106596 | RAL | 7 | 92394729 | plus | CDK6 | 4 bp (GGAC) | - |
HIV-1 DNA integratio sites were determined by LAM-PCR. LAM-PCR sequence were aligned to the human genome reference (GRCh37/hg19, Feb. 2009, UCSC). Chr, chromosome.