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. 1990 Jul;10(7):3852–3856. doi: 10.1128/mcb.10.7.3852

Transfected human beta-polymerase promoter contains a ras-responsive element.

P S Kedar 1, D R Lowy 1, S G Widen 1, S H Wilson 1
PMCID: PMC360856  PMID: 2192267

Abstract

beta-Polymerase is a vertebrate cellular DNA polymerase involved in gap-filling synthesis during some types of genomic DNA repair. We report that a cloned human beta-polymerase promoter in a transient expression assay is activated by p21v-rasH expression in NIH 3T3 cells. A decanucleotide palindromic element, GTGACGTCAC, at positions -49 to -40 in the promoter is required for this ras-mediated stimulation.

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Selected References

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