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European Spine Journal logoLink to European Spine Journal
. 2000 Oct;9(5):372–378. doi: 10.1007/s005860000203

Spinal fusions: bone and bone substitutes

D G Marchesi 1
PMCID: PMC3611386  PMID: 11057529

Abstract

Vertebral arthrodesis is one of the most commonly performed, yet incompletely understood, procedures in spinal surgery. Despite major progress in internal fixation techniques, the high rate of non-unions indicates that physiologic, biologic and molecular events that are crucial to this process are not well known. This article will analyze the general biology of bone regeneration, and particularly discuss the properties and use of various bone graft materials and graft substitutes.

Keywords: Key words Bone regeneration, Spinal fusion, Bone substitutes, Growth factors

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Footnotes

Received: 9 August 2000/Accepted: 11 August 2000


Articles from European Spine Journal are provided here courtesy of Springer-Verlag

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