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European Spine Journal logoLink to European Spine Journal
. 2001 Jul 17;10(6):473–481. doi: 10.1007/s005860100311

The pathogenesis of idiopathic scoliosis: uncoupled neuro-osseous growth?

Richard W Porter 1
PMCID: PMC3611539  PMID: 11806387

Abstract.

This paper examines the following speculative hypothesis: "that in some patients with scoliosis there is disproportionate neuro-osseous growth – the longitudinal growth of the spinal cord fails to keep pace with the growth of the vertebral column and, as a consequence, the spine buckles into a scoliosis deformity". A literature review of the morphology and neurology of scoliosis does not deny the hypothesis. Several mechanisms are suggested as to why the spinal cord growth could become uncoupled from osseous growth.

Keywords: Scoliosis Pathogenesis Spinal cord

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