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. 2000 Jul;24(3):155–157. doi: 10.1007/s002640000103

Nephrotoxicity by dicloxacillin and gentamicin in 163 patients with intertrochanteric hip fractures

L Solgaard 1, J I Tuxoe 1, M Mafi 1, S Due Olsen 1, T Toftgaard Jensen 1
PMCID: PMC3619878  PMID: 10990387

Abstract 

Of 163 patients with intertrochanteric hip fractures 87 received 2 g dicloxacillin and 240 mg of gentamicin preoperatively, and 76 patients had no antibiotic prophylaxis. Preoperative antibiotic prophylaxis was not shown to have any significant effect on wound infections. However, 16 reversible and 1 irreversible cases of kidney toxicity were found among patients receiving antibiotic prophylaxis, whereas there were only four cases of reversible kidney damage among the patients not receiving antibiotics.

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Footnotes

Accepted: 29 November 1999


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