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. 1989 Jan;9(1):303–311. doi: 10.1128/mcb.9.1.303

Anatomy of a new B-cell-specific enhancer.

W Koch 1, C Benoist 1, D Mathis 1
PMCID: PMC362173  PMID: 2467189

Abstract

The major histocompatibility complex class II molecules, like the immunoglobulins, are prominent B-lymphocyte markers. Herein, we describe a B-cell-specific enhancer associated with the murine class II gene, Ek alpha. This enhancer has a complex anatomy that suggests interactions between remotely spaced elements. Of particular interest is the finding that two CCAAT boxes spaced one kilobase apart are important for enhancer activity. Somewhat surprisingly, the E alpha and immunoglobulin enhancers seem to show little resemblance.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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