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. 1989 Jan;9(1):321–324. doi: 10.1128/mcb.9.1.321

An AP-2 element acts synergistically with the cyclic AMP- and phorbol ester-inducible enhancer of the human proenkephalin gene.

S E Hyman 1, M Comb 1, J Pearlberg 1, H M Goodman 1
PMCID: PMC362175  PMID: 2538722

Abstract

An enhancer with two DNA elements, one containing the sequence CGTCA, is required for cyclic AMP- and phorbol ester-inducible transcription of the human proenkephalin gene. We report that an AP-2 element located adjacent to the enhancer acts synergistically with it to confer maximal response to cyclic AMP and phorbol esters.

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Selected References

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