Table 1.

Association of oxidative stress related genes polymorphisms with changes in LFTs’ levels by consumption of silymarin

LFT	Gene	Unadjusted		Adjusted
		B (CI)	p-value	B (CI)	p-value
AST	NQO1	−0.73 (−3.38, 4.84)	0.72	−0.05 (−4.10, 3.92)	0.98
	GSTM1	−0.58 (−4. 02, 3.03)	0.75	−0.64 (−4.25, 2.97)	0.72
	GSTT1	1.27 (−3.10, 5.64)	0.56	1.92 (−2.55, 6.38)	0.40
	EPXH4	1.34 (−3.10, 5.77)	0.54	1.72 (−2.73, 6.17)	0.44
ALT	NQO1	0.87 (−4.20, 5.92)	0.73	0.79 (−4.40, 5.98)	0.76
	GSTM1	−4.24 (−8. 62, 0.13)	0.05	4.21 (−8.67, 0.25)	0.06
	GSTT1	1.30 (−4.23, 6.83)	0.64	1.22 (−4.50, 6.92)	0.65
	EPXH4	1.04 (−3.02, 4.67)	0.54	0.89 (−4.46, 6.24)	0.74
ALP	NQO1	−12.83 (−39.89, 14.22)	0.35	−2.64 (−20.22, 14.95)	0.76
	GSTM1	1.21 (−23.79, 26.21)	0.92	2.27 (−13.67, 18.22)	0.77
	GSTT1	21.28 (−8.93, 51.50)	0.16	10.21 (−9.46, 29.87)	0.30
	EPXH4	−14.20 (−47.62, 19.22)	0.40	1.73 (−17.78, 21.24)	0.86

Multivariate regression: Parameters adjusted for age and BMI;

B: Partial regression coefficient.