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. 2013 Feb 13;38(6):950–956. doi: 10.1038/npp.2012.256

Figure 3.

Figure 3

[3H]MeTRH binding to mouse brain membranes. Equal amounts of membrane protein were incubated at 4 °C with 2 nM [3H]MeTRH for 4 h without (Control) or with 30 μM MeTRH or 30 μM TAL. There was no difference in the binding in the presence of MeTRH or TAL. By t-test, specific binding (Control minus MeTRH) was found in membranes from WT and R2ko mice (***P<0.001) and in membranes from R1ko (++P<0.005), but not in membranes from R1/R2ko (P>0.1) mice. Data are shown as mean±SEM of five experiments.