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. 1989 May;9(5):2254–2257. doi: 10.1128/mcb.9.5.2254

Tissue-specific and hormonal regulation of the gene for rat prostatic steroid-binding protein in transgenic mice.

J Allison 1, Y L Zhang 1, M G Parker 1
PMCID: PMC363025  PMID: 2747651

Abstract

We investigated the tissue-specific and hormonal regulation of the gene for rat prostatic steroid-binding protein by introducing the C3(1) gene with 4-kilobase (kb) upstream and 2-kb downstream flanking sequences into transgenic mice. There was selective expression in the ventral prostate that was stimulated by testosterone, which indicated that the gene together with 6-kb flanking DNA contains the information required for prostate-specific and testosterone-regulated expression.

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Selected References

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