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. 1988 May;8(5):2251–2256. doi: 10.1128/mcb.8.5.2251

Detection of fos protein during osteogenesis by monoclonal antibodies.

P De Togni 1, H Niman 1, V Raymond 1, P Sawchenko 1, I M Verma 1
PMCID: PMC363412  PMID: 3133556

Abstract

We have generated monoclonal antibodies by using a synthetic peptide corresponding to amino acid positions 4 to 17 of the human fos protein. The antibodies detected both v- and c-fos proteins by immunoprecipitation, immunoblotting, and indirect immunofluorescence. The monoclonal antibodies not only identified the fos protein complex with the cellular 39-kilodalton protein, but also recognized the modified forms of the mouse, rat, and human fos proteins. In day-17 rat embryos, nuclear-staining fos protein could be identified in the cartilage by immunohistochemical staining.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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