Table 4.
Hazard analysis for the incidence of dry or wet AMD according to diabetic/diabetic retinopathy status from 1995–2005
| Dry AMD | Wet AMD | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Hazard Ratio (95% CI) for Development of Dry AMD | Hazard Ratio (95% CI) for Development of Wet AMD | |||||
| DM (n=6621) | NPDR (n=1307) | PDR (n=327) | DM (n=6621) | NPDR (n=1307) | PDR (n=327) | |
| Diabetes Subtype | 1.03 (0.97 1.09) | 1.24 (1.08 1.43) ** | 1.10 (0.83 1.47) | 1.11 (0.97 1.27) | 1.68 (1.23 2.31) ** | 2.15 (1.07 4.33) * |
|
| ||||||
| Age (years) | 1.07 (1.06 1.07) ** | 1.07 (1.06 1.09) ** | 1.06 (1.02 1.09) ** | 1.07 (1.05 1.08) ** | 1.08 (1.05 1.12) ** | 1.07 (0.99 1.16) |
| Male gender | 0.96 (0.90 1.03) | 0.75 (0.65 0.88) ** | 0.95 (0.70 1.30) | 0.99 (0.86 1.15) | 0.82 (0.59 1.13) | 1.38 (0.68 2.77) |
| Black race | 0.48 (0.41 0.56) ** | 0.37 (0.29 0.48) ** | 0.37 (0.22 0.63) ** | 0.35 (0.23 0.53) ** | 0.32 (0.17 0.59) ** | --- |
| Other race | 0.87 (0.72 1.04) | 0.73 (0.51 1.05) | 0.78 (0.40 1.53) | 0.51 (0.29 0.88) * | 0.37 (0.12 1.17) | 3.37 (1.26 9.01) ** |
| Hypertension | 1.01 (0.94 1.08) | 1.17 (0.99 1.39) | 0.92 (0.66 1.28) | 1.00 (0.86 1.17) | 1.05 (0.73 1.49) | 0.71 (0.33 1.51) |
| Atherosclerosis | 1.03 (0.94 1.14) | 1.00 (0.81 1.23) | 1.05 (0.71 1.55) | 1.13 (0.92 1.40) | 1.13 (0.73 1.75) | 0.78 (0.26 2.33) |
| Stroke | 1.11 (1.02 1.20) * | 0.93 (0.77 1.11) | 0.75 (0.53 1.06) | 1.06 (0.88 1.27) | 0.96 (0.65 1.42) | 0.58 (0.23 1.48) |
| Coronary heart disease | 1.04 (0.98 1.11) | 0.96 (0.83 1.11) | 1.04 (0.76 1.42) | 0.84 (0.72 0.98) * | 1.00 (0.73 1.37) | 0.80 (0.39 1.67) |
| Hyperlipidemia | 0.98 (0.92 1.04) | 0.93 (0.81 1.07) | 0.79 (0.58 1.07) | 0.87 (0.76 1.00) | 0.79 (0.58 1.08) | 1.37 (0.70 2.70) |
| Charlson Index | 1.01 (0.99 1.02) | 1.02 (0.99 1.05) | 1.06 (1.00 1.11) * | 1.02 (0.99 1.05) | 1.00 (0.94 1.07) | 1.01 (0.89 1.15) |
*
significant at the 5% level
**
significant at the 1% level
--- indicates sample size too small to register event