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. 1988 Aug;8(8):3553–3555. doi: 10.1128/mcb.8.8.3553

Presence of the adenovirus E1A-like activity in preimplantation stage mouse embryos.

H Suemori 1, S Hashimoto 1, N Nakatsuji 1
PMCID: PMC363595  PMID: 2974925

Abstract

The presence of the adenovirus E1A-like activity in embryonal carcinoma stem cells has been reported. We now show that preimplantation stage mouse embryonic cells allow transcription of the E1A-dependent E2A gene when infected with E1A-deleted mutant dl312, indicating the presence of the E1A-like activity in morulae and blastocysts. Moreover, such activity seems to decrease or disappear at about the time of implantation.

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Selected References

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