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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Surgery. 2012 Apr 11;152(1):114–122. doi: 10.1016/j.surg.2012.02.017

Fig. 2.

Fig. 2

Superiority of Ad 5/Ad 3 fiber-knob chimeric Ads for PDAc cell infection. Cancer cells were infected with a reporter vector under control of the ubiquitous CMV promoter with either the wild-type (Ad5) or Ad 5/Ad 3 fiber-knob chimeric (5/3) fiber. Results are shown as relative light units normalized to AdCMVLuc activity. The Ad5/3 fiber modification imparts significantly enhanced infectivity to all PDAc cell lines tested compared with the wild type. Asterisks indicate P <.05 for the comparison to Ad5 fiber.