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. Author manuscript; available in PMC: 2014 Jul 1.

Published in final edited form as: Biomaterials. 2013 Apr 8;34(21):5149–5162. doi: 10.1016/j.biomaterials.2013.03.044

Immunofluorescence staining of p53 in HepG2 cells at (a) one day, (b) three days, and (c) five days after commencement of treatment. The groups include blank and free drug groups as well as blank and drug loaded microsphere groups. The cell nuclei were stained by Hoechst dye and indicated in blue. The p53 was stained by DyLight^™ 549 dye and indicated in red. Scale bar = 50 μm.

Immunofluorescence staining of p53 in HepG2 cells at (a) one day, (b) three days, and (c) five days after commencement of treatment. The groups include blank and free drug groups as well as blank and drug loaded microsphere groups. The cell nuclei were stained by Hoechst dye and indicated in blue. The p53 was stained by DyLight^™ 549 dye and indicated in red. Scale bar = 50 μm.