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. Author manuscript; available in PMC: 2014 May 15.
Published in final edited form as: Cancer. 2013 Feb 21;119(10):1792–1799. doi: 10.1002/cncr.27893

Table 3.

Factors associated with RET/PTC or PAX8/PPARγ rearrangements in multivariate analysis

RET/PTC or
PAX8/PPARγ positive
RET/PTC or
PAX8/PPARγ negative
Characteristic % or mean (SD) % or mean (SD) OR 95% CI
I-131 dose, Gy
 0.008-<0.4 25.0 39.5 1.00 Referent
 0.4-<0.91 25.0 23.7 1.38 (0.28, 7.00)
 0.91-<1.63 25.0 10.5 2.47 (0.34, 19.05)
 1.63-8.60 25.0 26.3 0.77 (0.13, 4.13)
P trend 0.0191
Oblast of residence
 Chernihiv 45.8 57.9 1.00 Referent
 Kyiv 12.5 23.7 0.88 (0.13, 5.13)
 Zhytomyr 41.7 18.4 11.66 (2.22, 82.52)
P heterogeneity 0.007
Age at surgery, yr 22.6 (4.5) 25.8 (5.3) 0.79 (0.66, 0.91)
P trend 0.001
Sex
 Male 54.2 36.8 1.00 Referent
 Female 45.8 63.2 0.27 (0.06, 0.96)
P 0.043
1

Based on linear quadratic model (dose+dose2).