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. 1987 Feb;7(2):925–931. doi: 10.1128/mcb.7.2.925

The excised leader of human cytochrome c oxidase subunit I mRNA which contains the origin of mitochondrial DNA light-strand synthesis accumulates in mitochondria and is polyadenylated.

G Gaines, C Rossi, G Attardi
PMCID: PMC365152  PMID: 3029571

Abstract

We identified a polyadenylated RNA species which contains the origin of human mitochondrial DNA light-strand synthesis and the surrounding complementary sequences of the four light-strand-encoded tRNAs. This RNA (RNA 9L) is probably derived from the leader portion of RNA 6 which is excised during the formation of the mature cytochrome c oxidase subunit mRNA (RNA 9). The high degree of secondary structure of this RNA is presumably responsible for its anomalous electrophoretic behavior in denaturing polyacrylamide gels.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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