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. 1987 Mar;7(3):1276–1279. doi: 10.1128/mcb.7.3.1276

Episomal maintenance of a bovine papilloma virus vector in transgenic mice.

A Elbrecht, F J DeMayo, M J Tsai, B W O'Malley
PMCID: PMC365203  PMID: 3031486

Abstract

We have used a bovine papillomavirus-based vector to generate transgenic mice. Transgenic mice result from either pronuclear or cytoplasmic injections of the vector into fertilized eggs. Of 30 mice generated by microinjection, 27 (90%) contained the vector in its episomal form, at less than one copy per cell. This represents a highly efficient means of gene transfer in which the transgene is in a controlled genetic environment.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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