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. 1987 Mar;7(3):1280–1284. doi: 10.1128/mcb.7.3.1280

Human recipient cell for oncogene transfection studies.

M A Tainsky, F L Shamanski, D Blair, G Vande Woude
PMCID: PMC365204  PMID: 3470599

Abstract

We used human oncogene DNA to transform the nontumorigenic, revertant, human osteosarcoma cell line HOS TE-85 clone 5 (ATCC CRL 1543) to tumorigenicity in athymic nude mice with latency periods as short as 3 weeks. These cells were also transformed by genetic markers in genomic DNA samples. Because of their low rate of spontaneous tumor formation and the simplicity of culturing them, HOS cells provide a human cell alternative to NIH 3T3 murine fibroblasts for oncogene transfection studies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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