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. 1987 Apr;7(4):1563–1567. doi: 10.1128/mcb.7.4.1563

Context-dependent gene expression: cis-acting negative effects of specific procaryotic plasmid sequences on eucaryotic genes.

D O Peterson, K K Beifuss, K L Morley
PMCID: PMC365248  PMID: 3037330

Abstract

A sequence element within pBR322 DNA mediates a cis-acting negative effect on expression from eucaryotic genes in transient expression assays. The negative element overlaps with sequences that inhibit DNA replication, but its effect is observed in the absence of detectable replication of transfected DNA.

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Selected References

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