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. 1987 Apr;7(4):1572–1575. doi: 10.1128/mcb.7.4.1572

Unequal distribution of N6-methyladenosine in influenza virus mRNAs.

P Narayan, D F Ayers, F M Rottman, P A Maroney, T W Nilsen
PMCID: PMC365250  PMID: 3600638

Abstract

Influenza virus mRNA is posttranscriptionally methylated at internal adenosine residues to form N6-methyladenosine (m6A). It has been previously shown that there is an average of three m6A residues per influenza virus mRNA (R. M. Krug, M. A. Morgan, and A. J. Shatkin, J. Virol. 20:45-53, 1976). To determine the distribution of m6A in the different influenza virus mRNAs, we purified six of the mRNAs by hybrid selection, digested them with nuclease, and determined their methylation patterns by high-pressure liquid chromatography. The amount of m6A in the different mRNAs varied from one in matrix to eight in hemagglutinin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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