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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Cytotherapy. 2013 Mar 7;15(5):586–597. doi: 10.1016/j.jcyt.2013.01.006

Figure 1.

Figure 1

Bolus injection of naïve rat UCMSCs in tumors completely attenuated the growth of orthotopic Mat B III grafts in a syngeneic F344 rat model. A single intratumoral injection of rat UCMSCs (1 million cells, n = 9) significantly attenuated the Mat B III tumor growth curve (1 million Mat B III cells) and completely regressed the tumors at day 40 (A). Five each of rat UCMSC-treated or PBS-treated rats were sacrificed 14 days after tumor cell inoculation. The average tumor weight in rat UCMSC-treated rats was significantly smaller than in PBS-treated rats (n = 5) (B). *P < 0.05 compared with PBS-treated control.