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. 1988 Oct;8(10):4524–4528. doi: 10.1128/mcb.8.10.4524

Identification of a second interferon-regulated murine Mx gene.

P Staeheli 1, J G Sutcliffe 1
PMCID: PMC365528  PMID: 2460745

Abstract

The murine influenza virus resistance locus Mx consists of more than one interferon-responsive transcription unit. We isolated clones of the transcripts of a second Mx gene (Mx2) which is closely linked to the well-characterized resistance gene and determined their sequences. Mx2 mRNA is more than 90% identical to Mx1 mRNA in the region corresponding to the amino termini of the encoded proteins. Mx2 mRNAs of mouse strains BALB/c and CBA have open reading frames apparently interrupted by mutations. Interferon-treated cells from strain A2G and other influenza virus-resistant strains failed to express detectable amounts of Mx2 transcripts.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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