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. 1988 Oct;8(10):4557–4560. doi: 10.1128/mcb.8.10.4557

Estrogen-inducible binding of a nuclear factor to the vitellogenin upstream region.

O Bakker 1, J N Philipsen 1, B C Hennis 1, G Ab 1
PMCID: PMC365535  PMID: 3185560

Abstract

The estrogen-dependent binding of a protein to the upstream region of the chicken vitellogenin gene was detected by using in vivo dimethyl sulfate, genomic DNase I, and in vitro exonuclease III footprinting. The site is located between base pairs -848 and -824, and its sequence resembles that of the nuclear factor I binding site. The results suggest that a nuclear factor binding to this site is involved in the regulation of the vitellogenin gene.

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Selected References

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