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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Hypertension. 2013 Feb 25;61(4):842–849. doi: 10.1161/HYPERTENSIONAHA.111.00080

Figure 1.

Figure 1

The effect of bilateral PVN microinjections of p44/42 MAPK siRNA on ANG II-induced hypertension in rats. Daily mean blood pressure (MBP) and heart rate (HR) before and during systemic infusion of ANG II in rats treated early (A and B) or late (C and D) with p44/42 siRNA, a scrambled siRNA, or vehicle. Values are mean ± SEM (n = 5-6 for each group). *P< 0.05, vs. baseline; †P< 0.05, ANG II + p44/42 siRNA vs. ANG II + vehicle or ANG II + scrambled siRNA.