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. 1988 Nov;8(11):5047–5051. doi: 10.1128/mcb.8.11.5047

A silencer element from the alpha-globin gene inhibits expression of beta-like genes.

G F Atweh 1, J M Liu 1, H E Brickner 1, X X Zhu 1
PMCID: PMC365600  PMID: 2850473

Abstract

We have studied the cis and trans interactions of the alpha- and beta-globin genes in a transient expression system. We found that the alpha-globin gene inhibited beta-globin expression in cis but not in trans. The silencer element responsible for this inhibition was localized to a 259-base-pair fragment at the 5' end of the alpha-globin gene.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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