Table 1.
n (%) | Median | Range | |
---|---|---|---|
Age (years) | 43.6 | 23.9–62.3 | |
Men | 18 (60) | ||
Time between diagnosis and surgery (years) | 0.4 | 0–4.5 | |
Preoperative basal GH (mU/L) | 27 | 7.6–762.0 | |
Preoperative IGF-I (%ULN) | 316 | 184–539 | |
Tumor size > 10 mm | 27 (90) | ||
Received prior GH-lowering medication | 11 (37) | ||
Hypopituitarism (≥1 axis) | 9 (30) | ||
Hypogonadism | 7 (23) | ||
Hypocortisolism | 5 (17) | ||
Hypothyroidism | 4 (13) | ||
Diabetes insipidus | 0 (0) | ||
Symptoms at presentation | |||
Acral enlargement | 22 (76) | ||
Snoring | 13 (45) | ||
Macroglossia | 13 (45) | ||
Headache | 12 (41) | ||
Increased perspiration | 10 (35) | ||
Facial changes | 9 (31) | ||
Visual field defect | 7 (23) | ||
Other visual disturbance | 4 (13) |
ULN upper limit of normal range