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. 1972 Aug;50(2):224–227. doi: 10.1104/pp.50.2.224

Inhibition of Ribulose 1,5-Diphosphate Carboxylase by 6-Phosphogluconate 1

Douglas K Chu a, J A Bassham a
PMCID: PMC366114  PMID: 16658146

Abstract

6-Phosphogluconate is a much more effective inhibitor of the photosynthetic carboxylation enzyme, ribulose-1, 5-diphosphate carboxylase, than other sugar phosphates and sugar acids of the reductive and oxidative pentose phosphate cycles. The inhibition appears to be noncompetitive with ribulose 1,5-diphosphate. Since 6-phosphogluconate is unique to the oxidative cycle and inhibits at concentrations comparable to those found in vivo, it is proposed that its inhibition of the carboxylase may be a regulatory factor. If so, it would operate during darkness as a different control factor from those factors postulated to activate the carboxylase during photosynthesis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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