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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Drugs. 2013 Apr;73(5):407–426. doi: 10.1007/s40265-013-0038-y

Table V.

Hypothetical Studies of Smoker Subgroups; e.g.., Geno/Phenotypes (% denotes abstinence rates)

Hypothetical Study 1
Treatment A Treatment B RR (95% CI) p for interaction1
Subgroup 1 10% 40% 0.25 (.13 - .47) .0004
Subgroup 2 40% 42% 0.95 (.68–1.33)
Hypothetical Study 2
Subgroup 1 25% 40% 0.63 (.41 - .95) .7
Subgroup 2 30% 42% 0.74 (0.49–1.04)
1

Subgroup x treatment interaction