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. 2013 May 21;4(3):e00021-13. doi: 10.1128/mBio.00021-13

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Copyright © 2013 Napier et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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FIG 1 — Colistin resistance correlates with resistance to host cationic antimicrobials in A. baumannii clinical isolates. (A to J) Colistin-sensitive (A to D) and colistin-resistant (E to J) A. baumannii clinical isolates were treated with 6.25 µg/ml of LL-37 (green) or 2.5 mg/ml of lysozyme (blue) for the indicated times and plated for enumeration of CFU. Time zero CFU is indicated by dashed black lines. (K to L) Percent changes of CFU from time zero to 2 h after treatment with LL-37 (K) or lysozyme (L) from 4 individual experiments with 3 to 4 samples of each isolate represented in panels A to J. Data were analyzed for significance using the unpaired Student’s t test. **, P < 0.001; ***, P < 0.0001. Error bars represent the standard deviations of the results determined for triplicate samples.