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. 1985 Jan;5(1):242–247. doi: 10.1128/mcb.5.1.242

Increased secretion of type beta transforming growth factor accompanies viral transformation of cells.

M A Anzano, A B Roberts, J E De Larco, L M Wakefield, R K Assoian, N S Roche, J M Smith, J E Lazarus, M B Sporn
PMCID: PMC366699  PMID: 3856735

Abstract

Cells transformed by Harvey or Moloney sarcoma virus secrete at least 40 times as much type beta transforming growth factor as their respective untransformed control cells. The transformed cells bind only 20 to 50% as much type beta transforming growth factor as the control cells, suggesting that transformation causes down-regulation of the type beta transforming growth factor receptor.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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