Table 2.
Difference in BMI per 10 points of the weighted GRS according to average hours of TV watching*
| Average hours of TV watching per week |
P for Interaction | |||||
|---|---|---|---|---|---|---|
| 0-1 | 2-5 | 6-20 | 21-40 | ≥41 | ||
| Women | ||||||
| n | 439 | 1634 | 4003 | 1198 | 185 | |
| GRS (range) | 18.9-43.4 | 16.6-42.3 | 14.8-43.3 | 16.7-42.3 | 17.9-39.9 | |
| β (SE)† | ||||||
| Model 1‡ | 1.1 (0.6) | 1.3 (0.3) | 1.7 (0.2) | 1.6 (0.4) | 3.2 (1.2) | 0.05 |
| Model 2§ | 1.1 (0.6) | 1.2 (0.3) | 1.7 (0.2) | 1.6 (0.4) | 3.0 (1.1) | 0.05 |
| Men | ||||||
| n | 519 | 2231 | 1301 | 488 | 25 | |
| GRS (range) | 16.9-40.4 | 16.8-41.9 | 16.0-40.6 | 19.5-40.6 | 21.1-37.3 | |
| β (SE)† | ||||||
| Model 1‡ | 0.7 (0.4) | 0.7 (0.2) | 1.0 (0.2) | 1.3 (0.5) | 3.9 (2.1) | 0.04 |
| Model 2§ | 0.7 (0.4) | 0.7 (0.2) | 1.0 (0.2) | 1.3 (0.5) | 3.9 (2.2) | 0.05 |
| Pooled β (SE) † ¶ | ||||||
| Model 1‡ | 0.8 (0.4) | 0.8 (0.2) | 1.4 (0.2) | 1.5 (0.3) | 3.4 (1.0) | 0.001 |
| Model 2§ | 0.8 (0.4) | 0.8 (0.2) | 1.4 (0.2) | 1.5 (0.3) | 3.2 (1.0) | 0.001 |
*
Data are based on first 2 year of follow-up after the assessment of hours spent on TV watching in women (1992-1994) and men (1988-1990).
†
Difference in BMI (kg/m2) per 10 points of the weighted GRS.
‡
Adjusted for age, genotype data source and disease status.
§
Further adjusted for physical activity, smoking, alcohol intake, menopausal status (women only) and total energy intake.
¶
Results were pooled between women and men by inverse-variance–weighted, fixed-effects meta-analyses.