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. 1985 Aug;5(8):2150–2153. doi: 10.1128/mcb.5.8.2150

Interferon-induced human protein with homology to protein Mx of influenza virus-resistant mice.

P Staeheli, O Haller
PMCID: PMC366934  PMID: 3939324

Abstract

Polyclonal and monoclonal antibodies with specificity for protein Mx (a karyophilic 75,000-dalton protein induced by interferon [IFN] in mouse cells carrying the influenza virus resistance allele Mx+) detected an IFN-induced 80,000-dalton protein in peripheral blood lymphocytes and in fibroblasts of healthy human donors. The human protein, like protein Mx, was induced by IFN-alpha but not by IFN-gamma. Unlike the mouse protein, it was predominantly localized in the cell cytoplasm.

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Selected References

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