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. 2013 Jun;98(6):928–936. doi: 10.3324/haematol.2012.073585

Figure 2.

Figure 2.

Effect of PTEN inactivation and NOTCH1 activation on early treatment response in children with T-ALL. (A) Prednisone response: prednisone good response (PGR; <1000 blasts/μL of peripheral blood at Day 8), Prednisone poor response (PPR; ≥1000 blasts/μL of peripheral blood at Day 8). (B) MRD response on Day 33: an unfavorable MRD status (≥10−4) was defined by the presence of at least one leukemic cell in 104 cells, whereas a favorable MRD status (<10−4) was defined as the absence of detectable leukemic cells in 104 cells (C) MRD response on Day 78: an unfavorable MRD status (≥10−4) was defined by the presence of at least one leukemic cell in 104 cells, whereas a favorable MRD status (<10−4) was defined as the absence of detectable leukemic cells in 104 cells. The number of patients is indicated on top of the columns.