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. 1985 Oct;5(10):2866–2869. doi: 10.1128/mcb.5.10.2866

Interleukin 1 regulates human metallothionein gene expression.

M Karin, R J Imbra, A Heguy, G Wong
PMCID: PMC367029  PMID: 3879767

Abstract

Incubation of cultured human cells with interleukin 1 leads to increased expression of the human metallothionein-IIA gene. Recently, metallothionein has been shown to be an efficient free radical scavenger, and induction by interleukin 1 may be part of a protective response to minimize damage by hydroxyl radicals.

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Selected References

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