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. 1985 Jul;5(7):1804–1807. doi: 10.1128/mcb.5.7.1804

Expression of transfected DNA in avian cells can be enhanced in trans by retroviral infection.

B R Cullen, R A Katz, G Ju
PMCID: PMC367303  PMID: 2991753

Abstract

Using a quantitative S1 nuclease protection assay, we demonstrated that acute or chronic infection of avian cells enhances expression of an exogenously introduced rat preproinsulin II gene by approximately equal to 50-fold. The degree of enhancement is shown to vary with the transfection technique used but is independent of the transcription control region of the transfected gene. We conclude that retroviral infection of avian cells enhances expression of transfected DNA in trans by facilitating the uptake of DNA rather than by activating the transfected promoter.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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