Skip to main content
NIHPA Author Manuscripts logoLink to NIHPA Author Manuscripts
. Author manuscript; available in PMC: 2013 Jun 5.
Published in final edited form as: Child Adolesc Psychiatr Clin N Am. 2010 Jul;19(3):625–641. doi: 10.1016/j.chc.2010.03.012

Non-substance Addictive Behaviors in Youth: Pathological Gambling and Problematic Internet Use

Christina Brezing 1, Jeffrey L Derevensky 2, Marc N Potenza 3
PMCID: PMC3673531  NIHMSID: NIHMS467596  PMID: 20682225

Introduction

Despite differences with respect to their respective histories, gambling and internet use may share similarities with respect to representing two behaviors in which adolescents routinely participate. This manuscript will review youth participation in gambling and internet use, describe when such participation may become problematic, and summarize current prevention and treatment strategies for pathological gambling (PG) and problematic internet use (PIU) in youth.

Definitions

Gambling and internet use exist as a spectrum of behaviors ranging from abstinence to recreational participation to problematic engagement, with the extreme end including the disorders of PG and PIU. How PG and PIU are defined in adolescents has significant implications for prevalence estimates in this group. Currently, there exists variability across studies that measure the prevalence of these disorders in youth, with differences in how these problems are defined and measured thought to contribute to the observed variability. There exist formal diagnostic criteria for PG in the DSM-IV-TR that states an individual with PG must have at least five inclusionary criteria reflective of impaired control over gambling behaviors that are associated with significant life disruption and/or negative psychosocial impact (American Psychiatric Association). PG typically involves strong motivations to engage in gambling, with elements of withdrawal and craving representing similarities with substance dependence reflected in the diagnostic criteria for the disorders. Researchers have proposed a number of subtypes of problem gambling based on a pathways model that identifies individuals as behaviorally conditioned, emotionally vulnerable, or antisocial impulsive 1. These proposed adult-based definitions may not necessarily apply to adolescents with PG given differences in adolescents and adults. As adults and adolescents have different roles and life experiences, PG may present and impact these groups in different ways 2. A recent study attempting to validate this model with adolescents yielded some mixed results 3.

Arguably the most commonly used definition of PIU is based on the DSM-IV-TR definition of PG. The following definition suggests that PIU shares many features with impulse control disorders and substance dependence; PIU reflects impaired control over the “use of the internet that leads to significant psychosocial and functional impairments, and this pattern of use is not better accounted for by a primary psychiatric disorder such as mania or the physiological effects of a substance” 4, 5. It is important to distinguish PIU from normal internet use, other Axis I disorders and compulsive-impulsive behaviors 6. This process may prove difficult, however, as PIU may involve online gambling, internet-enabled sexual behavior, and online gaming—behaviors that exist on a spectrum from innocuous to pathological and may themselves constitute impulse control disorders. For this reason, some have described the internet as an “electronic needle” that provides an anonymous, socially connected, novel media 7 to allow participation in impulse control disorders. It has been proposed that PIU may be sub-typed based on specific behaviors forming the focus of the PIU 8, although systematic studies describing potential differences in the clinical characteristics of individuals with PIU segregated by these behaviors are currently lacking. There exist clinical characteristics that all forms of PIU seem to share that help to identify them as one general disorder with different manifestations. These characteristics were developed from observations largely derived from case reports of individuals with PIU, and the extent to which they represent generalizable clinically meaningful criteria warrants further investigation. The clinical characteristics include: time spent on internet exceeding 35hrs/week and longer than initially intended and planned, time distortion, compulsive behaviors, unsuccessful attempts with cessation or controlling use, deception about extent of use, utilization of the internet behavior to cope or escape problems, and preoccupation with the internet when offline 5, 6, 9, 10. These PIU behaviors have been proposed to be representative of a “technological addiction” and fall under the larger category of “behavioral” addictions, which has been proposed to include PG 11, 12. However, disorders considered “behavioral” or non-substance addictions are currently categorized in the DSM-IV-TR as impulse control disorders not elsewhere classified. The DSM-IV-TR does not currently define specific diagnostic criteria for PIU but the disorder can be diagnosed as an impulse control disorder not otherwise specified.

Forms of PG and PIU and Their Addictive Potentials

Adolescents engage in multiple forms of regulated and non-regulated gambling including cards, bets with friends, sports betting, lottery purchases, and poker playing. The forms of gambling in which individuals participate may often be dependent upon the individual’s gender, age, cultural and ethnic background, availability and accessibility. It has been proposed that forms of gambling that are continuous in nature and require an element of skill may have a stronger association with PG 13, although others have proposed that non-strategic forms of gambling like electronic gambling (slot) machines may be more “addictive” 14. Some individuals have proposed that features of electronic gambling machines (potential for rapid gambling, relatively high event frequencies, intermittent reinforcement schedules) as well as ancillary features (sounds, music, and lights) may keep people, especially adolescents, entertained and engaged 13,15,16. The fact that many of theses machines incorporate video game technology may add to their appeal. However, a growing body of data do not uniformly indicate that specific forms of gambling have greater addictive potential, including among adolescents 14, 17. While many regulated forms of gambling legally restrict minors from participation, adolescents often acknowledge gambling on both regulated and non-regulated activities for their age group 18, 19.

Adolescents with PIU engage in a number of internet behaviors, with common forms being gambling, internet enabled sexual behavior, and online gaming. Several large-scale studies exist for problematic online gambling and suggest that online gamblers may be more likely to have PG than offline gamblers 20. The internet may provide access for adolescents and young adults 21, 22 as one study found that 25% of college students have wagered on the internet 23. It is difficult to determine the prevalence and extent of internet enabled sexual behavior (IESB), but internet pornography grosses over $1 billion per year 4. Online gaming may provide a social and interactive environment for adolescents, and adolescents and young adults may devote substantial time to massive multiplayer online games to the extent of neglecting important areas of life functioning 4.

Prevalence

Although the prevalence estimates of PG and PIU are not precisely known, the disorders are believed to occur internationally and affect all ages, genders, and ethnic groups. It has been estimated that the prevalence of PG and serious problem gambling is two to four-fold higher in youth aged 12-17 years, than the prevalence in the adult population, with an additional 10-14% of adolescents considered “at risk” for developing PG later in life 24, 25. Studies have estimated adult prevalence of PG at 1-2%, while estimating the adolescent PG rates at 3-8% 26. The prevalence of gambling participation in teens may also be increasing over time with some researchers noting increases from 45% to 66% 27-29, and others estimating even higher prevalences of juvenile gambling ranging up to 91% participation 30, 31. Some researchers contend these estimates are accurate 26, and others suggest these rates may be inflated and that the trajectory of prevalence estimates over time are relatively stable 32. Data in support of this notion that early estimates might be inflated come from recent studies in adults in which diagnostic assessments of PG were obtained rather than relying on screening instruments (which by design are developed to over-identify possible cases minimizing the risks of false negatives) to ascertain prevalence estimates. Several large, well-controlled studies using diagnostic assessments have estimated past-year PG to range from 0.1% to 0.3%, with lifetime estimates two- to three-fold higher 33-35. However, as subsyndromal levels of gambling have been associated with adverse measures of functioning in both adolescents and adults 36, 37, more research is needed to investigate the precise prevalence and clinical implications of both syndromal and subsyndromal PG.

The prevalence of PIU in adolescents is also not precisely known and may be more difficult to determine than that for PG. Inconsistent assessment instruments, lack of formal diagnostic criteria, a focus primarily on young populations, and sampling of sections of the general population complicate conclusions that can be drawn regarding the prevalence and impact of PIU. Current assessment tools include the Diagnostic Questionnaire 5 and Internet Addiction Test 38, instruments whose reliability and validity have been preliminarily tested, and many other instruments whose validity and reliability have yet to be empirically validated. These tools, while helpful in identifying individuals with PIU, may not replace a formal diagnostic clinical interview 4, 39. Large scale offline community studies in Finland, Norway, and South Korea estimate a prevalence of PIU of 2% in adolescents 4, 40, and PIU is believed to represent a serious public health issue, particularly in regions of Asia including South Korea, Taiwan, and China 41. Arguably the best current estimate of the prevalence of PIU comes from a study that used 4 positive indicators for internet overuse as a screening tool for PIU 42. Aboujaoude et al. found that in a population of individuals 18yrs and older, that 0.7% had 4 positive indicators, with 3.7-13.7% having 1-3 positive indicators. The study was interpreted to suggest that approximately 1% of the adult population may have narrow or “severe” PIU with another 4-14% possibly having problems with internet overuse. The precise estimates in adolescents warrant direct examination, and given changes in internet technologies and usage over time, longitudinal studies appear warranted.

Factors that may influence prevalence

Environmental Factors

The interaction of the environment with individual differences factors may influence the likelihood of developing PG or PIU. Some studies have suggested a link between the availability and accessibility of gambling and rates of gambling and PG 18, 43. Some investigators have proposed that there has been an increase in overall gambling rates in conjunction with increasing gambling availability 44. In addition, new technological forms, for example internet gambling, allow for solitary and unsupervised gambling. Advertising campaigns for gambling may target youth directly or indirectly, encouraging gambling participation while utilizing names and characters popular with adolescents 18. Some have predicted that internet gambling may increase ten-fold in the near future 45. The extent to which PIU, particularly amongst youth, may become more prevalent over time is difficult to predict, and direct investigation of PIU, in conjunction with factors that may be hypothesized to influence PIU, is indicated.

Social, Demographic, and Cultural Factors

Family and Peer Influences

Familial factors may significantly influence adolescent behavior 13. There may be a widespread perception that gambling is acceptable and normal, and youths’ initial experiences with gambling may often occur within their homes 46. Parental and older sibling attitudes towards gambling may impact youth involvement, and adolescents with gambling problems are more likely to have parents who are perceived to gamble excessively, have other addictive behaviors, or participate in illegal activities 30, 47, 48. Adolescents with parents who are ambivalent about youth gambling appear to have an approximately 50% greater probability of significant gambling problems 43. In a recent Canadian national study, it was found that parents rated gambling least problematic among 13 potential adolescent behaviors (e.g., alcohol, drug and cigarette smoking, use, unprotected sex, etc.) 49. Peer influence also warrants consideration. Up to 44% of adolescents report having gambled because of the influence of friends 50, and, as children age, a significant venue of choice for gambling may be in their homes with friends 46. Social factors appear particularly relevant in adolescent gambling, perhaps even more so than other factors (e.g., gambling to win money) that may be more salient for older age groups 51. Gambling has been reported to give children the perception of feeling older and a way to show their skills to friends 52 and there exists a strong social learning component involved in some gambling behaviors 53. Overall, adolescents often view gambling as benign and less harmful than alcohol, drugs, and cigarettes 54, and youth attitudes and behavior may predict patterns of gambling in adulthood 45. Little data are available regarding family and peer influences on PIU and future studies are needed to elucidate their influence on internet behaviors.

Gender Differences

Among youth, the ratio of males to females with PG is approximately 3-5:1 24. Boys as compared with girls typically report higher gross wagers and increased risk taking behavior and begin gambling earlier, on more games and more often, commit more time and money to gambling, and experience more gambling related problems 24, 55. Some have proposed this pattern to result from parents encouraging boys to participate in gambling more than girls 56, creating an environment where gambling is a significant part of male culture 57. However, gambling amongst girls is more closely linked to symptoms of depression that amongst boys 37, perhaps because boys may tend to use gambling as a form of avoidance coping and an escape strategy more so than girls do 58. Amongst adults with gambling problems, men tend to have problems with “face-to-face” forms of gambling (poker, blackjack) and substance abuse problems and criminal behaviors while women have tend to develop problems with less personally interactive forms of gambling (bingo, electronic gambling machines) and are more likely to receive non-gambling related mental health services 59.

Like in PG, there is a male preponderance for PIU in adolescents. Boys as compared to girls tend to engage in computer activities associated with strong emotional-motivational states and are more likely to take part in the activities common in PIU including online games, cybersex, and gambling 40, 60. The gender-related differences in these behavioral syndromes suggest that there may exist different underlying motivations for participation that ultimately may require different prevention and treatment strategies.

Cultural Differences

Cultural and ethnic backgrounds have been shown to influence gambling behaviors. A study in Minnesota high-school students demonstrated that American Indians (30%) and Mexican Americans and African Americans (22%) gamble at greater weekly and daily rates than Asian and Caucasian Americans (4-5%) 19. Additional studies have similarly found that Hispanic Americans, African Americans, and American Indian adolescents gamble at greater rates than Caucasian Americans 61, 62. Although existing studies have not directly examined cultural and ethnic differences in adolescents with respect to PIU, numerous studies and clinical reports have suggested that PIU may be a significant public health concern among specific Asian cultures.

Physiological and Personality Factors

There is evidence to suggest that individual physiological and personality characteristics may predispose some individuals to PG. Adolescents with PG have been found to have increased physiological resting states, greater sensation seeking, and greater arousability and excitability related to gambling 1. Youth with PG also tend to dissociate more frequently while they participate in gambling behaviors 28, 30, 63. Specific personality features suggest adolescent gamblers have been found to display more risk-taking behaviors 1, 13 and score higher on measures of impulsivity 46, extroversion, and state and trait anxiety 64. They may also exhibit more self-blaming, guilt, anxiety and emotional lability 65. Gambling and/or PG among adolescents has also been shown to be associated with lower conformity and self-discipline scores 30 and increased frequency of attention deficit hyperactivity disorder (ADHD), conduct-related problems 48, antisocial behaviors, and alcohol and substance abuse 48, 66, 67. Youth with PG also have maladaptive coping skills 1 that may be an important mediating factor as adolescents use gambling to help dissociate and escape from stressful events using money simply as a means to the end goal of continued playing 30, 58. Although less research has been performed into physiological and personality factors associated with adolescent PIU, the disorder has also been conceptualized within a stress-coping framework 4, 68.

Age of Onset and Course of Disorder

The average time of first gambling experience has been reported as twelve years of age, an age considerably younger the first use of alcohol, tobacco or other drugs 24. Adolescents with PG usually initiate in gambling behaviors even earlier, at approximately 10 years of age, compared to peers without problematic behaviors 69. Initiation of gambling in youth has been associated with an increased likelihood of a substance use problem to begin during young adulthood 66. Age of onset has been suggested to predict more severe problems later in life 70.

Compared to adults, adolescents may progress more rapidly from social forms of gambling to PG, chase losses more consistently, and have erroneous perceptions when gambling 53, 71. Data indicate that early signs of impulsive behavior and ADHD are associated with excessive gambling involvement in adolescence and early adulthood 72,73. These early signs of impulsive behavior and ADHD may also be associated with addictive behavioral syndromes like PG and PIU in adolescence and resultant adult behavior.

PIU has been reported in children as young as six years of age 4. It has been suggested that children and adolescents may be at increased risk for developing PIU, and anecdotal evidence suggests that the time of onset of PIU from first internet use is often within the first six months, giving rise to the term, “the newbie syndrome” 5. After an individual develops PIU, behaviors may lead to decreased offline social activities and increased depression and loneliness over the course of several years 74. PIU may represent a chronic disorder with remissions and recurrences 75, although systematic longitudinal studies to support this notion are lacking.

Neurobiology

Adolescence and Impulsivity

Impulsivity is a construct with relevance to PG and multiple other psychiatric conditions 2, 76. Impulsivity may be conceptualized as a disturbance in reward motivation 77 and identified through risk-taking 76. Gambling involves ritualized risk-taking and, therefore, impulsive individuals may be predisposed to gambling 2. Impulsive individuals may fail to change risk-taking behaviors in the setting of past losses or assess risks appropriately, and thus individuals may demonstrate a lack of inhibition and a greater propensity to discount delayed rewards at an excessive rate 2, 78.

Adolescence, as a developmental stage, has often been associated with increased impulsivity 2. One hypothesis regarding increased impulsivity during adolescence implicates the immaturity of the frontal cortical and subcortical monoamine systems during this developmental period 2, 65, 79, 80. Such immaturity may influence decision-making to allow for optimal learning drive during this developmental period, with dopamine and serotonin representing two contributing neurotransmitters. Dopamine discharge in the striatum may act to facilitate the action of a motivated drive in association with a reward benefit: (1) in the short term as a “go signal” for a motivated drive to result in behavior; and, (2) in the long term to create neuroplastic changes underlying motivational memory and repertoire. Dopamine function within the nucleus accumbens may promote a range of motivated behaviors 81,82, 83, with the short-term reward mechanism functioning such that events that are novel, salient, rewarding or unpredictable are identified and given behavioral responses 83-85. Neurodevelopmental changes within cortico-striatal functioning thus may contribute to impulsivity and PG during adolescence 2, 83, 85.

Prefrontal cortical networks have been proposed to limit control motivational drives. Serotonin systems, comprised of serotonin tracts emanating from the raphe nuclei and synapsing into the prefrontal cortex, have been proposed to contribute importantly to this process 2, 80. Central markers for serotonin are decreased in individuals with impulse control disorders including PG 86, and prefrontal cortex compromise is associated with disadvantageous decision-making and engagement in seemingly impulsive behaviors 87, 88. In normal development, substantial changes occur in the prefrontal cortex during adolescence and this may reflect a relatively diminished ability to exhibit self-control. The combination of changes within dopamine and serotonin systems and cortico-striatal circuitry during adolescence may reflect a greater susceptibility to engagement in impulse control disorders like PG and PIU 2, although longitudinal biological investigations to directly investigate this hypothesis are warranted.

Unlike PG, there are limited biological data on PIU. The neurobiology may share similarities with those for substance abuse and impulse control disorders like PG, although currently there lacks direct evidence. Some research has suggested that adolescents with PIU have higher impulsivity than controls 89, but other studies have shown mixed results. It has been proposed that internet use is a goal-directed behavior controlled by the ventral tegmental area projections to the nucleus accumbens that may become aberrantly active leading to PIU 4, 90, 91. One study using naltrexone, an opioid receptor antagonist, successfully treated internet enabled sexual behavior 92. This finding seems to suggest that medication may indirectly target dopamine function in the mesolimbic dopamine, thus being helpful for a broad range of impulse control disorders including PG and PIU 93, 94. Individuals with PIU who demonstrate excessive online gaming show increased emotional arousal and stronger cortical reactivity in response to computer game visual cues with increased urges to play, suggesting that gaming urges/cravings may share similar biological features with substance abuse craving 95. Empirical investigations comparing these conditions are warranted to examine this hypothesis.

Comorbidities

Both PG and PIU are associated with multiple psychiatric conditions. There is a strong association of substance abuse and dependence and PG. The increased occurrence of alcohol and tobacco use in teens with PG suggests the two disorders may share a similar etiology 96, 97. Shared neural features have been found in association with cocaine cravings and gambling urges 86, and a twin study with alcohol and PG suggest a common genetic vulnerability 98. In addition to substance abuse, PG has also been found to be associated with psychotic disorders, internalizing disorders (forms of depression and anxiety), and personality disorders 2, 35, 99-101. PG has been associated with suicidal ideation and attempts 1 and behavioral problems including increased delinquent and criminal behavior, poor school performance, and disrupted family and peer relationships 48.

Although less is currently known about the pathology of PIU, it is associated with co-occurring disorders, particularly depression 4. A quarter of adolescents with PIU experience major depression 102, and up to 70% of individuals with PIU have been diagnosed with bipolar I or II at some point in their lives 103. PIU may lead to isolation and depression, and the severity of depression may be correlated with the degree of internet use. It is also hypothesized that the excessive depression may lead to PIU when internet use is used as a coping strategy 74. PIU has also been associated with ADHD. One study found that of 500 Korean students, 22.5% with PIU had ADHD, and it has been suggested that adult ADHD may be the best predictor of PIU among college students 104, 105. Obsessive-compulsive disorder (OCD) and other impulse control disorders have also been associated with PIU in small samples 103. PIU has also associated with heavy alcohol use in college students 106. PIU may occur with social phobia and is believed to contribute to heavier internet use but may not explain the compulsive pattern of use seen in PIU 103. Unlike PG, psychotic disorders appear less common in PIU.

Prevention

Many prevention strategies for PG are based on approaches used in alcohol and substance abuse prevention and utilize the concept of risk and protective factors and their resultant interaction. Risk factors for future gambling problems may include impulsivity, early age of initiation (before 12 years old), being male, prior substance misuse, low scores on measures of resiliency and poor family and school connectedness 30, 58, 70, 107. These factors are associated with adolescent risk behavior in general and have been applied to PG. At this point, there is insufficient information to develop a full list of protective factors for PG, but family cohesion has been reported to be a protective factor 54, 108. A goal of prevention strategies involves limiting the effects of putative risk factors while enhancing resiliency through enhancing protective factors. In doing so, PG is approached through a harm-reduction and minimization strategy—typically not involving abstinence but rather promoting responsible gambling. Abstinence models prohibit youth from legally accessing regulated gambling activities, and while stricter enforcements and adherence may be required, it has already been found that many youth still access and participate in gambling with prohibitive policies in place. For this reason, it seems reasonable to target informed use and utilize Beck’s approach of “just say know” (1998) rather than a “just say no” approach. Canada’s prevention efforts focused at the McGill University Centre for Youth Problem Gambling and High Risk Behaviors has adopted and paved the way for a risk-protective factor model by including efforts to bring multi-media prevention programs to elementary students since reports of gambling begin early, often in children aged 9 and 10 years old 30, 31. It is important to consider appropriate regulation and enforcement approaches to the prevention of youth gambling by advocating informed use 109. For example, current adolescent opinion reflects that participating in the lottery is not gambling 18 so one approach would focus on disseminating and communicating information and strategies that create more realistic understandings of and attitudes towards gambling 110, 111. Direct examination of the effectiveness of prevention strategies for adolescent gambling and PG is needed as substance abuse prevention programs with seemingly logical tenets have not been found to be uniformly successful 112.

Currently, there is a little known about the risk and protective factors in PIU making the development of an effective prevention strategy difficult. A recent study found that depression and low-family monitoring were discriminating factors for PIU in adolescents regardless of age or gender, with low connectedness to school, high family conflict, peers with habitual alcohol use, and rural living environments also associated with PIU 113. These data suggest that parents might increase home monitoring of internet use and aid youth in seeking treatment for depression to help prevent PIU.

Treatment

Evidenced-based treatments for PG have been reported, with advances over the past decade seen for both pharmacological and behavioral therapies for PG 94, 114. However, these approaches have largely been tested in adults with PG, and relatively few studies have systematically examined their efficacies and tolerabilities in youths 115. Challenges related to lack of perceived gambling problems amongst youth identified via screening instruments as having them in conjunction with infrequent treatment seeking further complicate the treatment of adolescent PG 116, 117.

Data suggest that different types of adolescent gambling might require consideration in treatment development 1, 73, 118. The pathways approach that defines behaviorally conditioned, emotionally vulnerable, and antisocial impulsive gamblers may have important implications for both the diagnosis and treatment of PG and suggests that a dynamic and interactive strategy that takes into account the multi-factorial nature of the disorder may be most therapeutic 1, 65. Direct examination of this hypothesis in both adolescent and adult samples is warranted.

Both behavioral and pharmacological treatments for adult PG have shown initial positive results in controlled trials. Behavioral approaches including cognitive behavioral therapy, motivational interviewing, brief counseling, and imaginal desensitization have all shown initial positive results, as have attendance in self-help programs (specifically Gamblers Anonymous)94, 119. However, these approaches have largely not been systematically tested in youth populations. The transtheoretical model of intentional behavioral change has also been suggested to serve as a framework for treatment paradigm of adolescent PG 27, 120-122. Psychopharmacological approaches using serotonin reuptake inhibitors, mood stabilizers, opioid antagonists and glutamatergic agents have shown efficacy and tolerability in controlled trials in adults with PG, albeit not uniformly with all classes 94. Precise pharmacological recommendations for adolescents must wait until controlled treatment studies are performed 115, 123-125. As adolescents may not actively seek treatment, outreach programs (including telephone counseling and home-based treatment manuals) have been suggested 121, 122. Treatment approaches should consider addressing other co-occurring or underlying psychological problems that exist in addition to PG 126, particularly as PG and other impulse control disorders may go unidentified in youth with psychiatric concerns. Although adolescence typically involves a relatively narrow range of ages (12-17 years), there is great variability in maturity and different treatments should consider their appropriateness within a developmental framework 65.

The lack of uniformly agreed upon, formalized diagnostic criteria and valid and reliable assessment instruments for PIU make designing and measuring treatment paradigms and their efficacies and tolerabilities difficult. Nonetheless, there exist a growing number of outpatient treatment services including those at the Computer Addiction Study Center at Mclean Hospital of Harvard Medical School, the Illinois institute for Addiction Recovery at Proctor Hospital, and a halfway house for adolescents with PIU in China. The goal in treatment for PIU in these programs is typically controlled use, not abstinence. Treatment for adolescents might include family based interventions, skills for parents to improve communication, and increased monitoring of internet use 127. A study of cognitive behavioral therapy utilizing a daily log in conjunction with software to restrict access showed improvement in symptoms but appeared poorly generalized 8. Motivational interviewing utilizing the transtheoretical model of behavioral change 128 and studies using both cognitive behavioral therapy and motivational interviewing showed improvements in quality of life and depression but no significant changes in computer use behaviors 92. Insight orient psychotherapy has also been suggested as a model for treatment. Internet support groups may also serve a role in the treatment of PIU. On-line support groups provide wide accessibility and incorporate a medium that is familiar to these individuals. The extent to which these approaches might be helpful for youth with PIU warrants direct examination in controlled trials.

Psychopharmacology has been examined in some individuals with PIU. An open label study in 19 patients given a serotonin reuptake inhibitor showed decreased time spent online, decreased impulsivity and compulsivity, and increased overall global function 90. Additionally, a case report demonstrated improvement in an online gambler with depression treated with a serotonin reuptake inhibitor 129 and atypical antipsychotics, such as quitiepine, may offer augmentation strategies 9. Naltrexone has also been successfully used to treat three of four men with PIU. Controlled trials are indicated to determine the extent to which these medications might be helpful, and direct examination with specific age groups is indicated to examine their efficacies and tolerabilities in a developmentally informed fashion.

PG and PIU share common negative consequences including disrupted interpersonal relationships, increased delinquent and criminal behavior, poor work and school performance, and greater social isolation 30, 130. Future directions in treatment-focused studies should further identify specific factors that motivate individuals with PG and PIU to engage excessively in gambling and internet use, respectively. If these factors can be more precisely defined, clinical interventions may be designed to build resiliency such that individuals susceptible to PG and PIU may be better able to cope with adversity.

Conclusions

PG and subsyndromal gambling have been shown to be associated with adverse measures of functioning in youth and older individuals. Although PIU may share similarities with PG with respect to developmental impacts, few studies, particularly longitudinal ones, have been conducted to test this hypothesis. PG and PIU represent important and potentially growing public health issues that may go unrecognized by clinicians who focus on more “visible” behaviors such as drug and alcohol abuse. Parents, educators, clinicians and public health officials should address PG and PIU in youth before they escalate. As various treatments for PG and PIU may not translate across developmental groups, direct examination of their efficacies and tolerabilities are warranted in youths. Similarly, although prevention strategies from other fields (e.g., prevention of youth risk behaviors, including substance use and abuse) may be adopted and modified for PG and PIU, direct examination of their effectiveness is needed.

Synopsis.

Adolescence is characterized by participation in multiple novel and potentially risky behaviors. Amongst these behaviors are gambling and use of the internet, and excessive engagement in these activities (as seen in pathological gambling and problematic internet use) may be accompanied by serious impairments in school, mental health and social functioning. Here we review the potential impact of pathological gambling and problematic internet use in youth, the relevance of subsyndromal levels of participation, and how prevention and treatment strategies may be considered and tested within a developmental framework.

Acknowledgments

Funding Sources and Disclosures This work was supported by the National Institutes of Health (NIH) grants R01 DA019039, R01 RL1 AA017539, P50 DA09241, P50 DA016556, UL1 DE19586, NIH Roadmap for Medical Research/Common Fund, the Office of Research on Women’s Health, and a Center of Excellence on Gambling Research Award from the National Center for Responsible Gaming and its affiliated affiliated Institute for Research on Gambling Disorders. The contents of the manuscript are solely the responsibility of the authors and do not necessarily represent the official views of any of the funding agencies. Dr. Potenza has received financial support or compensation for the following: Dr. Potenza consults for and is an advisor to Boehringer Ingelheim; has consulted for and has financial interests in Somaxon; has received research support from the National Institutes of Health, Veteran’s Administration, Mohegan Sun Casino, the National Center for Responsible Gaming and its affiliated Institute for Research on Gambling Disorders, and Forest Laboratories, Ortho-McNeil, Oy-Control/Biotie and Glaxo-SmithKline pharmaceuticals; has participated in surveys, mailings or telephone consultations related to drug addiction, impulse control disorders or other health topics; has consulted for law offices and the federal public defender’s office in issues related to impulse control disorders; provides clinical care in the Connecticut Department of Mental Health and Addiction Services Problem Gambling Services Program; has performed grant reviews for the National Institutes of Health and other agencies; has given academic lectures in grand rounds, CME events and other clinical or scientific venues; and has generated books or book chapters for publishers of mental health texts.

Dr. Derevensky has received research support from the Social Sciences Humanities Research Council in Canada, Ministry of Health and Social Services, Quebec, Nova Scotia Gaming Corporation, Ontario Problem Gambling Research Center and has consulted to a number of government bodies internationally. He has also performed research reviews for groups in Europe, North America, Asia, Australia, New Zealand, and South Africa.

Footnotes

Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

References

  • 1.Nower L, Derevensky JL, Gupta R. The relationship of impulsivity, sensation seeking, coping, and substance use in youth gamblers. Psychol Addict Behav. 2004;18(1):49–55. doi: 10.1037/0893-164X.18.1.49. [DOI] [PubMed] [Google Scholar]
  • 2.Chambers RA, Potenza MN. Neurodevelopment, impulsivity, and adolescent gambling. J Gambl Stud. 2003;19(1):53–84. doi: 10.1023/a:1021275130071. [DOI] [PubMed] [Google Scholar]
  • 3.Gupta R, Nower L, Derevensky J, et al. Problem gambling in adolescents: An examination of the Pathways Model. Report prepared for the Ontario Problem Gambling Research Center; Ontario: 2009. [DOI] [PubMed] [Google Scholar]
  • 4.Liu T, Potenza MN. Problematic Internet use: clinical implications. CNS Spectr. 2007;12(6):453–66. doi: 10.1017/s1092852900015339. [DOI] [PubMed] [Google Scholar]
  • 5.Young KS. Psychology of computer use: XL. Addictive use of the Internet: a case that breaks the stereotype. Psychol Rep. 1996;79(3 Pt 1):899–902. doi: 10.2466/pr0.1996.79.3.899. [DOI] [PubMed] [Google Scholar]
  • 6.Shapira NA, Lessig MC, Goldsmith TD, et al. Problematic internet use: proposed classification and diagnostic criteria. Depress Anxiety. 2003;17(4):207–16. doi: 10.1002/da.10094. [DOI] [PubMed] [Google Scholar]
  • 7.Miller MC. Questions & answers. Is “Internet addiction” a distinct mental disorder? Harv Ment Health Lett. 2007;24(4):8. [PubMed] [Google Scholar]
  • 8.Young KS. Cognitive behavior therapy with Internet addicts: treatment outcomes and implications. Cyberpsychol Behav. 2007;10(5):671–79. doi: 10.1089/cpb.2007.9971. [DOI] [PubMed] [Google Scholar]
  • 9.Atmaca M. A case of problematic internet use successfully treated with an SSRI-antipsychotic combination. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31(4):961–62. doi: 10.1016/j.pnpbp.2007.01.003. [DOI] [PubMed] [Google Scholar]
  • 10.Allison SE, von Wahlde L, Shockley T, et al. The development of the self in the era of the internet and role-playing fantasy games. Am J Psychiatry. 2006;163(3):381–85. doi: 10.1176/appi.ajp.163.3.381. [DOI] [PubMed] [Google Scholar]
  • 11.Griffiths M. Nicotine, tobacco and addiction. Nature. 1996;384(6604):18. doi: 10.1038/384018a0. [DOI] [PubMed] [Google Scholar]
  • 12.Griffiths M. Psychology of computer use: XLIII. Some comments on ‘addictive use of the Internet’ by Young. Psychol Rep. 1997;80(1):81–2. doi: 10.2466/pr0.1997.80.1.81. [DOI] [PubMed] [Google Scholar]
  • 13.Abbott MW, Volberg RA, Ronnberg S. Comparing the New Zealand and Swedish national surveys of gambling and problem gambling. J Gambl Stud. 2004;20(3):237–58. doi: 10.1023/B:JOGS.0000040278.08853.c0. [DOI] [PubMed] [Google Scholar]
  • 14.Dowling N, Smith D, Thomas T. Electronic gaming machines: are they the ‘crack-cocaine’ of gambling? Addiction. 2005;100(1):33–45. doi: 10.1111/j.1360-0443.2005.00962.x. [DOI] [PubMed] [Google Scholar]
  • 15.Griffiths M. Gambling Technologies: Prospects for Problem Gambling. J Gambl Stud. 1999;15(3):265–83. doi: 10.1023/a:1023053630588. [DOI] [PubMed] [Google Scholar]
  • 16.Wood RT, Griffiths MD. Adolescent lottery and scratchcard players: do their attitudes influence their gambling behaviour? J Adolesc. 2004;27(4):467–75. doi: 10.1016/j.adolescence.2003.12.003. [DOI] [PubMed] [Google Scholar]
  • 17.Welte JW, Barnes GM, Tidwell MC, et al. The association of form of gambling with problem gambling among American youth. Psychol Addict Behav. 2009;23(1):105–12. doi: 10.1037/a0013536. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 18.Felsher JR, Derevensky JL, Gupta R. Lottery playing amongst youth: implications for prevention and social policy. J Gambl Stud. 2004;20(2):127–53. doi: 10.1023/B:JOGS.0000022306.72513.7c. [DOI] [PubMed] [Google Scholar]
  • 19.Stinchfield R. Gambling and correlates of gambling among Minnesota public school students. J Gambl Stud. 2000;16(2-3):153–73. doi: 10.1023/a:1009428913972. [DOI] [PubMed] [Google Scholar]
  • 20.McBride J, Derevensky J. Internet gambling behaviour in a sample of online gamblers. Int J of Mental Health and Addiction. 2009;7:149–67. [Google Scholar]
  • 21.Labrie RA, Laplante DA, Nelson SE, et al. Assessing the Playing Field: A Prospective Longitudinal Study of Internet Sports Gambling Behavior. J Gambl Stud. 2007 doi: 10.1007/s10899-007-9067-3. [DOI] [PubMed] [Google Scholar]
  • 22.Labrie RA, Kaplan SA, Laplante DA, et al. Inside the virtual casino: a prospective longitudinal study of actual Internet casino gambling. Eur J Public Health. 2008;18(4):410–16. doi: 10.1093/eurpub/ckn021. [DOI] [PubMed] [Google Scholar]
  • 23.Petry NM, Weinstock J. Internet gambling is common in college students and associated with poor mental health. Am J Addict. 2007;16(5):325–30. doi: 10.1080/10550490701525673. [DOI] [PubMed] [Google Scholar]
  • 24.Jacobs DF. Youth gambling in North America: Long-term trends and future prospects. In: Derevensky JaG R, editor. Gambling Problems in Youth: Theoretical and Applied Perspectives. Klewer Academic/Plenum Publishers; New York, NY: 2004. pp. 1–24. [Google Scholar]
  • 25.Pathological gambling: A critical review. National Academy Press; Washington, D.C.: 1999. [PubMed] [Google Scholar]
  • 26.Derevensky JL, Gupta R, Winters K. Prevalence rates of youth gambling problems: are the current rates inflated? J Gambl Stud. 2003;19(4):405–25. doi: 10.1023/a:1026379910094. [DOI] [PubMed] [Google Scholar]
  • 27.DiClemente CC, Story M, Murray K. On a roll: the process of initiation and cessation of problem gambling among adolescents. J Gambl Stud. 2000;16(2-3):289–13. doi: 10.1023/a:1009441216698. [DOI] [PubMed] [Google Scholar]
  • 28.Jacobs DF. Juvenile gambling in North America: an analysis of long term trends and future prospects. J Gambl Stud. 2000;16(2-3):119–52. doi: 10.1023/a:1009476829902. [DOI] [PubMed] [Google Scholar]
  • 29.Shaffer HJ, Hall MN. Updating and refining prevalence estimates of disordered gambling behaviour in the United States and Canada. Can J Public Health. 2001;92(3):168–72. doi: 10.1007/BF03404298. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 30.Gupta R, Derevensky JL. Adolescent Gambling Behavior: A Prevalence Study and Examination of the Correlates Associated with Problem Gambling. J Gambl Stud. 1998;14(4):319–45. doi: 10.1023/a:1023068925328. [DOI] [PubMed] [Google Scholar]
  • 31.Derevensky JL, Gupta R. Prevalence estimates of adolescent gambling: a comparison of the SOGS-RA, DSM-IV-J, and the GA 20 questions. J Gambl Stud. 2000;16(2-3):227–51. doi: 10.1023/a:1009485031719. [DOI] [PubMed] [Google Scholar]
  • 32.Ladouceur R, Jacques C, Chevalier S, et al. Prevalence of pathological gambling in Quebec in 2002. Can J Psychiatry. 2005;50(8):451–56. doi: 10.1177/070674370505000804. [DOI] [PubMed] [Google Scholar]
  • 33.Gerstein D, Hoffman J, Larison C, et al. Gambling impact and behavior study: National Opinion Research Center. University of Chicago; 1999. [Google Scholar]
  • 34.Kessler RC, Hwang I, LaBrie R, et al. DSM-IV pathological gambling in the National Comorbidity Survey Replication. Psychol Med. 2008;38(9):1351–60. doi: 10.1017/S0033291708002900. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 35.Petry NM, Stinson FS, Grant BF. Comorbidity of DSM-IV pathological gambling and other psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry. 2005;66(5):564–74. doi: 10.4088/jcp.v66n0504. [DOI] [PubMed] [Google Scholar]
  • 36.Desai RA, Potenza MN. Gender differences in the associations between past-year gambling problems and psychiatric disorders. Soc Psychiatry Psychiatr Epidemiol. 2008;43(3):173–83. doi: 10.1007/s00127-007-0283-z. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 37.Desai RA, Maciejewski PK, Pantalon MV, et al. Gender differences in adolescent gambling. Ann Clin Psychiatry. 2005;17(4):249–58. doi: 10.1080/10401230500295636. [DOI] [PubMed] [Google Scholar]
  • 38.Widyanto L, McMurran M. The psychometric properties of the internet addiction test. Cyberpsychol Behav. 2004;7(4):443–50. doi: 10.1089/cpb.2004.7.443. [DOI] [PubMed] [Google Scholar]
  • 39.Beard KW. Internet addiction: a review of current assessment techniques and potential assessment questions. Cyberpsychol Behav. 2005;8(1):7–14. doi: 10.1089/cpb.2005.8.7. [DOI] [PubMed] [Google Scholar]
  • 40.Johansson A, Gotestam KG. Internet addiction: characteristics of a questionnaire and prevalence in Norwegian youth (12-18 years) Scand J Psychol. 2004;45(3):223–29. doi: 10.1111/j.1467-9450.2004.00398.x. [DOI] [PubMed] [Google Scholar]
  • 41.Block JJ. Issues for DSM-V: internet addiction. Am J Psychiatry. 2008;165(3):306–7. doi: 10.1176/appi.ajp.2007.07101556. [DOI] [PubMed] [Google Scholar]
  • 42.Aboujaoude E, Koran LM, Gamel N, et al. Potential markers for problematic internet use: a telephone survey of 2,513 adults. CNS Spectr. 2006;11(10):750–55. doi: 10.1017/s1092852900014875. [DOI] [PubMed] [Google Scholar]
  • 43.Fisher S. Measuring the prevalence of sector-specific problem gambling: a study of casino patrons. J Gambl Stud. 2000;16(1):25–51. doi: 10.1023/a:1009479300400. [DOI] [PubMed] [Google Scholar]
  • 44.Korn DA, Shaffer HJ. Gambling and the Health of the Public: Adopting a Public Health Perspective. J Gambl Stud. 1999;15(4):289–365. doi: 10.1023/a:1023005115932. [DOI] [PubMed] [Google Scholar]
  • 45.Griffiths M, Wood RT. Risk factors in adolescence: the case of gambling, videogame playing, and the internet. J Gambl Stud. 2000;16(2-3):199–225. doi: 10.1023/a:1009433014881. [DOI] [PubMed] [Google Scholar]
  • 46.Gupta R, Derevensky J. Familial and social influences on juvenile gambling behavior. J Gambl Stud. 1997;13(3):179–92. doi: 10.1023/a:1024915231379. [DOI] [PubMed] [Google Scholar]
  • 47.Ladouceur R, Jacques C, Ferland F, et al. Parents’ Attitudes and Knowledge Regarding Gambling Among Youths. J Gambl Stud. 1998;14(1):83–90. doi: 10.1023/a:1023002826778. [DOI] [PubMed] [Google Scholar]
  • 48.Hardoon KK, Gupta R, Derevensky JL. Psychosocial variables associated with adolescent gambling. Psychol Addict Behav. 2004;18(2):170–79. doi: 10.1037/0893-164X.18.2.170. [DOI] [PubMed] [Google Scholar]
  • 49.Derevensky J, Campbell C, Meerkamper E, et al. Parental attitudes towards youth gambling: Results from a national Canadian study. Paper presented at the National Council on Problem Gambling annual conference; Indianapolis, IN. 2009. [Google Scholar]
  • 50.Griffiths MD. Adolescent gambling: an observational pilot study. Percept Mot Skills. 1990;70(3 Pt 2):1138. doi: 10.2466/pms.1990.70.3c.1138. [DOI] [PubMed] [Google Scholar]
  • 51.Burge AN, Pietrzak RH, Petry NM. Pre/early adolescent onset of gambling and psychosocial problems in treatment-seeking pathological gamblers. J Gambl Stud. 2006;22(3):263–74. doi: 10.1007/s10899-006-9015-7. [DOI] [PubMed] [Google Scholar]
  • 52.Fisher S. Gambling and pathological gambling in adolescents. Journal of Gambling Studies. 1993;9:277–88. [Google Scholar]
  • 53.Hardoon KK, Derevensky JL. Social influences involved in children’s gambling behavior. J Gambl Stud. 2001;17(3):191–215. doi: 10.1023/a:1012216305671. [DOI] [PubMed] [Google Scholar]
  • 54.Dickson LM, Derevensky JL, Gupta R. The prevention of gambling problems in youth: a conceptual framework. J Gambl Stud. 2002;18(2):97–159. doi: 10.1023/a:1015557115049. [DOI] [PubMed] [Google Scholar]
  • 55.Derevensky J, Gupta R, Della-Cioppa G. A developmental perspective of gambling behavior in children and adolescents. Journal of Gambling Studies. 1996;12:49–66. doi: 10.1007/BF01533189. [DOI] [PubMed] [Google Scholar]
  • 56.Ladouceur R, Dube D, Bujold A. Prevalence of pathological gambling and related problems among college students in the Quebec metropolitan area. Can J Psychiatry. 1994;39(5):289–93. doi: 10.1177/070674379403900509. [DOI] [PubMed] [Google Scholar]
  • 57.Huxley J, Carroll D. A survey of fruit machine gambling in adolescence. Journal of Gambling Studies. 1992;8:167–79. doi: 10.1007/BF01014634. [DOI] [PubMed] [Google Scholar]
  • 58.Bergevin T, Gupta R, Derevensky J, et al. Adolescent Gambling: Understanding the Role of Stress and Coping. J Gambl Stud. 2006 doi: 10.1007/s10899-006-9010-z. [DOI] [PubMed] [Google Scholar]
  • 59.Potenza MN, Steinberg MA, McLaughlin SD, et al. Gender-related differences in the characteristics of problem gamblers using a gambling helpline. Am J Psychiatry. 2001;158(9):1500–5. doi: 10.1176/appi.ajp.158.9.1500. [DOI] [PubMed] [Google Scholar]
  • 60.Ko CH, Yen JY, Yen CF, et al. Screening for Internet addiction: an empirical study on cut-off points for the Chen Internet Addiction Scale. Kaohsiung J Med Sci. 2005;21(12):545–51. doi: 10.1016/S1607-551X(09)70206-2. [DOI] [PubMed] [Google Scholar]
  • 61.Stinchfield R, Cassuto N, Winters K, et al. Prevalence of gambling among Minnesota public school students in 1992 and 1995. J Gambl Stud. 1997;13(1):25–48. doi: 10.1023/a:1024987131943. [DOI] [PubMed] [Google Scholar]
  • 62.Wallisch L. Gambling in Texas: 1992 Texas survey of adolescent gambling behavior. Austin, TX: 1993. [Google Scholar]
  • 63.Powell J, Hardoon K, Derevensky JL, et al. Gambling and risk-taking behavior among university students. Subst Use Misuse. 1999;34(8):1167–84. doi: 10.3109/10826089909039402. [DOI] [PubMed] [Google Scholar]
  • 64.Blaszczynski A, McConaughy N. The medical model of pathological gambling: Current shortcomings. Journal of Gambling Behavior. 1989;5:42–52. [Google Scholar]
  • 65.Gupta R, Derevensky JL. Adolescents with gambling problems: from research to treatment. J Gambl Stud. 2000;16(2-3):315–42. doi: 10.1023/a:1009493200768. [DOI] [PubMed] [Google Scholar]
  • 66.Lynch WJ, Maciejewski PK, Potenza MN. Psychiatric correlates of gambling in adolescents and young adults grouped by age at gambling onset. Arch Gen Psychiatry. 2004;61(11):1116–22. doi: 10.1001/archpsyc.61.11.1116. [DOI] [PubMed] [Google Scholar]
  • 67.Winters KC, Anderson N. Gambling involvement and drug use among adolescents. J Gambl Stud. 2000;16(2-3):175–98. doi: 10.1023/a:1009480930810. [DOI] [PubMed] [Google Scholar]
  • 68.Ha JH, Kim SY, Bae SC, et al. Depression and Internet addiction in adolescents. Psychopathology. 2007;40(6):424–30. doi: 10.1159/000107426. [DOI] [PubMed] [Google Scholar]
  • 69.Wynne H, Smith G, Jacobs D. Adolescent gambling and problem gambling in Alberta. Alberta, CA: 1996. [Google Scholar]
  • 70.Winters KC, Stinchfield RD, Botzet A, et al. A prospective study of youth gambling behaviors. Psychol Addict Behav. 2002;16(1):3–9. doi: 10.1037//0893-164x.16.1.3. [DOI] [PubMed] [Google Scholar]
  • 71.Derevensky J, Gupta R, Dickson L. Prevention efforts toward reducing gambling problems. In: Derevensky J, Gupta R, editors. Gambling Problems in Youth: Theoretical and Applied Perspectives. Klewer Academic/Plenum Publishers; New York, NY: 2004. pp. 211–30. [Google Scholar]
  • 72.Pagani LS, Derevensky JL, Japel C. Predicting gambling behavior in sixth grade from kindergarten impulsivity: a tale of developmental continuity. Arch Pediatr Adolesc Med. 2009;163(3):238–43. doi: 10.1001/archpediatrics.2009.7. [DOI] [PubMed] [Google Scholar]
  • 73.Vitaro F, Wanner B, Ladouceur R, et al. Trajectories of gambling during adolescence. J Gambl Stud. 2004;20(1):47–69. doi: 10.1023/B:JOGS.0000016703.84727.d3. [DOI] [PubMed] [Google Scholar]
  • 74.Kraut R, Patterson M, Lundmark V, et al. Internet paradox. A social technology that reduces social involvement and psychological well-being? Am Psychol. 1998;53(9):1017–31. doi: 10.1037//0003-066x.53.9.1017. [DOI] [PubMed] [Google Scholar]
  • 75.Ko CH, Yen JY, Yen CF, et al. Factors predictive for incidence and remission of internet addiction in young adolescents: a prospective study. Cyberpsychol Behav. 2007;10(4):545–51. doi: 10.1089/cpb.2007.9992. [DOI] [PubMed] [Google Scholar]
  • 76.Evenden J. Impulsivity: a discussion of clinical and experimental findings. J Psychopharmacol. 1999;13(2):180–92. doi: 10.1177/026988119901300211. [DOI] [PubMed] [Google Scholar]
  • 77.Zuckerman M. P-impulsive sensation seeking and its behavioral, psychophysiological and biochemical correlates. Neuropsychobiology. 1993;28(1-2):30–6. doi: 10.1159/000118996. [DOI] [PubMed] [Google Scholar]
  • 78.Reynolds B. A review of delay-discounting research with humans: relations to drug use and gambling. Behav Pharmacol. 2006;17(8):651–67. doi: 10.1097/FBP.0b013e3280115f99. [DOI] [PubMed] [Google Scholar]
  • 79.Ernst M, Nelson EE, Jazbec S, et al. Amygdala and nucleus accumbens in responses to receipt and omission of gains in adults and adolescents. Neuroimage. 2005;25(4):1279–91. doi: 10.1016/j.neuroimage.2004.12.038. [DOI] [PubMed] [Google Scholar]
  • 80.Casey BJ, Getz S, Galvan A. The adolescent brain. Dev Rev. 2008;28(1):62–77. doi: 10.1016/j.dr.2007.08.003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 81.Cardinal RN, Pennicott DR, Sugathapala CL, et al. Impulsive choice induced in rats by lesions of the nucleus accumbens core. Science. 2001;292(5526):2499–501. doi: 10.1126/science.1060818. [DOI] [PubMed] [Google Scholar]
  • 82.Pennartz CM, Groenewegen HJ, Lopes da Silva FH. The nucleus accumbens as a complex of functionally distinct neuronal ensembles: an integration of behavioural, electrophysiological and anatomical data. Prog Neurobiol. 1994;42(6):719–61. doi: 10.1016/0301-0082(94)90025-6. [DOI] [PubMed] [Google Scholar]
  • 83.Chambers RA, Bickel WK, Potenza MN. A scale-free systems theory of motivation and addiction. Neurosci Biobehav Rev. 2007;31(7):1017–45. doi: 10.1016/j.neubiorev.2007.04.005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 84.Ferster CB. Concurrent schedules of reinforcement in the chimpanzee. Science. 1957;125(3257):1090–1. doi: 10.1126/science.125.3257.1090. [DOI] [PubMed] [Google Scholar]
  • 85.Waelti P, Dickinson A, Schultz W. Dopamine responses comply with basic assumptions of formal learning theory. Nature. 2001;412(6842):43–8. doi: 10.1038/35083500. [DOI] [PubMed] [Google Scholar]
  • 86.Potenza MN. The neurobiology of pathological gambling and drug addiction: an overview and new findings. Philos Trans R Soc Lond B Biol Sci. 2008;363(1507):3181–9. doi: 10.1098/rstb.2008.0100. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 87.Bechara A. Neurobiology of decision-making: risk and reward. Semin Clin Neuropsychiatry. 2001;6(3):205–16. doi: 10.1053/scnp.2001.22927. [DOI] [PubMed] [Google Scholar]
  • 88.Bechara A, Damasio H, Damasio AR, et al. Different contributions of the human amygdala and ventromedial prefrontal cortex to decision-making. J Neurosci. 1999;19(13):5473–81. doi: 10.1523/JNEUROSCI.19-13-05473.1999. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 89.Cao F, Su L, Liu T, Gao X. The relationship between impulsivity and Internet addiction in a sample of Chinese adolescents. Eur Psychiatry. 2007;22(7):466–71. doi: 10.1016/j.eurpsy.2007.05.004. [DOI] [PubMed] [Google Scholar]
  • 90.Dell’Osso B, Altamura AC, Allen A, et al. Epidemiologic and clinical updates on impulse control disorders: a critical review. Eur Arch Psychiatry Clin Neurosci. 2006;256(8):464–75. doi: 10.1007/s00406-006-0668-0. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 91.Liu CY, Kuo FY. A study of Internet addiction through the lens of the interpersonal theory. Cyberpsychol Behav. 2007;10(6):799–804. doi: 10.1089/cpb.2007.9951. [DOI] [PubMed] [Google Scholar]
  • 92.Orzack MH, Voluse AC, Wolf D, et al. An ongoing study of group treatment for men involved in problematic Internet-enabled sexual behavior. Cyberpsychol Behav. 2006;9(3):348–60. doi: 10.1089/cpb.2006.9.348. [DOI] [PubMed] [Google Scholar]
  • 93.Kim SW. Opioid antagonists in the treatment of impulse-control disorders. J Clin Psychiatry. 1998;59(4):159–64. [PubMed] [Google Scholar]
  • 94.Brewer JA, Grant JE, Potenza MN. The treatment of pathological gambling. Addict Disorders Treatment. 2008;7:1–14. [Google Scholar]
  • 95.Ko CH, Liu GC, Hsiao S, et al. Brain activities associated with gaming urge of online gaming addiction. J Psychiatr Res. 2009;43(7):739–47. doi: 10.1016/j.jpsychires.2008.09.012. [DOI] [PubMed] [Google Scholar]
  • 96.Blanco C, Moreyra P, Nunes EV, et al. Pathological gambling: addiction or compulsion? Semin Clin Neuropsychiatry. 2001;6(3):167–76. doi: 10.1053/scnp.2001.22921. [DOI] [PubMed] [Google Scholar]
  • 97.Potenza MN. The neurobiology of pathological gambling. Semin Clin Neuropsychiatry. 2001;6(3):217–26. [PubMed] [Google Scholar]
  • 98.Slutske WS, Eisen S, True WR, et al. Common genetic vulnerability for pathological gambling and alcohol dependence in men. Arch Gen Psychiatry. 2000;57(7):666–73. doi: 10.1001/archpsyc.57.7.666. [DOI] [PubMed] [Google Scholar]
  • 99.Potenza MN, Chambers RA. Schizophrenia and pathological gambling. Am J Psychiatry. 2001;158(3):497–8. doi: 10.1176/appi.ajp.158.3.497-a. [DOI] [PubMed] [Google Scholar]
  • 100.Potenza MN, Xian H, Shah K, et al. Shared genetic contributions to pathological gambling and major depression in men. Arch Gen Psychiatry. 2005;62(9):1015–21. doi: 10.1001/archpsyc.62.9.1015. [DOI] [PubMed] [Google Scholar]
  • 101.Desai RA, Potenza MN. A cross-sectional study of problem and pathological gambling in patients with schizophrenia/schizoaffective disorder. J Clin Psychiatry. 2009:e1–e8. doi: 10.4088/JCP.08m04359. epub ahead of print. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 102.Ha JH, Yoo HJ, Cho IH, et al. Psychiatric comorbidity assessed in Korean children and adolescents who screen positive for Internet addiction. J Clin Psychiatry. 2006;67(5):821–6. doi: 10.4088/jcp.v67n0517. [DOI] [PubMed] [Google Scholar]
  • 103.Shapira NA, Goldsmith TD, Keck PE, et al. Psychiatric features of individuals with problematic internet use. J Affect Disord. 2000;57(1-3):267–72. doi: 10.1016/s0165-0327(99)00107-x. [DOI] [PubMed] [Google Scholar]
  • 104.Yoo HJ, Cho SC, Ha J, et al. Attention deficit hyperactivity symptoms and internet addiction. Psychiatry Clin Neurosci. 2004;58(5):487–94. doi: 10.1111/j.1440-1819.2004.01290.x. [DOI] [PubMed] [Google Scholar]
  • 105.Yen JY, Yen CF, Chen CS, et al. The association between adult ADHD symptoms and internet addiction among college students: the gender difference. Cyberpsychol Behav. 2009;12(2):187–91. doi: 10.1089/cpb.2008.0113. [DOI] [PubMed] [Google Scholar]
  • 106.Yen JY, Ko CH, Yen CF, et al. The association between harmful alcohol use and Internet addiction among college students: comparison of personality. Psychiatry Clin Neurosci. 2009;63(2):218–24. doi: 10.1111/j.1440-1819.2009.01943.x. [DOI] [PubMed] [Google Scholar]
  • 107.Lussier I, Derevensky JL, Gupta R, et al. Youth gambling behaviors: an examination of the role of resilience. Psychol Addict Behav. 2007;21(2):165–73. doi: 10.1037/0893-164X.21.2.165. [DOI] [PubMed] [Google Scholar]
  • 108.Jessor R, Turbin MS, Costa FM. Protective factors in adolescent health behavior. J Pers Soc Psychol. 1998;75(3):788–800. doi: 10.1037//0022-3514.75.3.788. [DOI] [PubMed] [Google Scholar]
  • 109.Felsher J, Derevensky J, Gupta R. Parental influences and social modeling of youth lottery participation. Journal of Community and Applied Social Psychology. 2003;13:361–77. [Google Scholar]
  • 110.Ferland F, Ladouceur R, Vitaro F. Prevention of problem gambling: modifying misconceptions and increasing knowledge. J Gambl Stud. 2002;18(1):19–29. doi: 10.1023/a:1014528128578. [DOI] [PubMed] [Google Scholar]
  • 111.Ferland F, Ladouceur R, Vitaro F. [Efficiency of a gambling prevention program for youths: results from the pilot study] Encephale. 2005;31(4 Pt 1):427–36. doi: 10.1016/s0013-7006(05)82404-2. [DOI] [PubMed] [Google Scholar]
  • 112.Clayton RR, Cattarello AM, Johnstone BM. The effectiveness of Drug Abuse Resistance Education (project DARE): 5-year follow-up results. Prev Med. 1996;25(3):307–18. doi: 10.1006/pmed.1996.0061. [DOI] [PubMed] [Google Scholar]
  • 113.Yen CF, Ko CH, Yen JY, et al. Multi-dimensional discriminative factors for Internet addiction among adolescents regarding gender and age. Psychiatry Clin Neurosci. 2009;63(3):357–64. doi: 10.1111/j.1440-1819.2009.01969.x. [DOI] [PubMed] [Google Scholar]
  • 114.Toneatto T, Ladoceur R. Treatment of pathological gambling: a critical review of the literature. Psychol Addict Behav. 2003;17(4):284–92. doi: 10.1037/0893-164X.17.4.284. [DOI] [PubMed] [Google Scholar]
  • 115.Grant JE. Pharmacological treatment of adolescent problem gambling. Int J Adol Med Health. in press. [PMC free article] [PubMed] [Google Scholar]
  • 116.Hardoon K, Derevensky JL, Gupta R. Empirical measures vs. perceived gambling severity among youth: why adolescent problem gamblers fail to seek treatment. Addict Behav. 2003;28(5):933–46. doi: 10.1016/s0306-4603(01)00283-0. [DOI] [PubMed] [Google Scholar]
  • 117.Cronce JM, Corbin WR, Steinberg MA, et al. Self-perception of gambling problems among adolescents identified as at-risk or problem gamblers. J Gambl Stud. 2007;23(4):363–75. doi: 10.1007/s10899-006-9053-1. [DOI] [PubMed] [Google Scholar]
  • 118.Toneatto T, Millar G. Assessing and treating problem gambling: empirical status and promising trends. Can J Psychiatry. 2004;49(8):517–25. doi: 10.1177/070674370404900803. [DOI] [PubMed] [Google Scholar]
  • 119.Grant JE, Donahue CB, Odlaug BL, et al. Imaginal desensitisation plus motivational interviewing for pathological gambling: randomised controlled trial. Br J Psychiatry. 2009;195(3):266–7. doi: 10.1192/bjp.bp.108.062414. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 120.DiClemente CC, Schlundt D, Gemmell L. Readiness and stages of change in addiction treatment. Am J Addict. 2004;13(2):103–19. doi: 10.1080/10550490490435777. [DOI] [PubMed] [Google Scholar]
  • 121.Hodgins DC, el-Guebaly N. Natural and treatment-assisted recovery from gambling problems: a comparison of resolved and active gamblers. Addiction. 2000;95(5):777–89. doi: 10.1046/j.1360-0443.2000.95577713.x. [DOI] [PubMed] [Google Scholar]
  • 122.Hodgins DC, Currie SR, el-Guebaly N. Motivational enhancement and self-help treatments for problem gambling. J Consult Clin Psychol. 2001;69(1):50–7. doi: 10.1037//0022-006x.69.1.50. [DOI] [PubMed] [Google Scholar]
  • 123.Grant JE, Potenza MN. Impulse control disorders: clinical characteristics and pharmacological management. Ann Clin Psychiatry. 2004;16(1):27–34. doi: 10.1080/10401230490281366. [DOI] [PubMed] [Google Scholar]
  • 124.Grant JE, Potenza MN. Escitalopram treatment of pathological gambling with co-occurring anxiety: an open-label pilot study with double-blind discontinuation. Int Clin Psychopharmacol. 2006;21(4):203–9. doi: 10.1097/00004850-200607000-00002. [DOI] [PubMed] [Google Scholar]
  • 125.Toneatto T, Brands B, Selby P. A randomized, double-blind, placebo-controlled trial of naltrexone in the treatment of concurrent alcohol use disorder and pathological gambling. Am J Addict. 2009;18(3):219–25. doi: 10.1080/10550490902787007. [DOI] [PubMed] [Google Scholar]
  • 126.Grant JE, Williams KA, Potenza MN. Impulse-control disorders in adolescent psychiatric inpatients: co-occurring disorders and sex differences. J Clin Psychiatry. 2007;68(10):1584–92. doi: 10.4088/jcp.v68n1018. [DOI] [PubMed] [Google Scholar]
  • 127.Yen JY, Yen CF, Chen CC, et al. Family factors of internet addiction and substance use experience in Taiwanese adolescents. Cyberpsychol Behav. 2007;10(3):323–9. doi: 10.1089/cpb.2006.9948. [DOI] [PubMed] [Google Scholar]
  • 128.Prochaska JO, DiClemente CC, Velicer WF, Rossi JS. Criticisms and concerns of the transtheoretical model in light of recent research. Br J Addict. 1992;87(6):825–8. doi: 10.1111/j.1360-0443.1992.tb01973.x. [DOI] [PubMed] [Google Scholar]
  • 129.Sattar P, Ramaswamy S. Internet gaming addiction. Can J Psychiatry. 2004;49(12):869–70. [PubMed] [Google Scholar]
  • 130.McBride J. Virtual interaction is still social interaction: How massively multiplayer online role-playing games and online gambling blur the distinction between normal and excessive Internet use. McGill University; Montreal, Canada: 2009. [Google Scholar]

RESOURCES