Table 2.

—Spearman Correlation Coefficients Between SGRQ Scores and Anchors at Baseline, 6 Months, and 12 Months

Domain	Symptom	Activity	Impact	Total
FEV1%
Baseline	−0.33 (.002)	−0.35 (.0007)	−0.26 (.01)	−0.33 (.001)
6 mo	−0.41 (.0001)	−0.48 (< .0001)	−0.42 (< .0001)	−0.49 (< .0001)
12 mo	−0.35 (.002)	−0.46 (< .0001)	−0.29 (.01)	−0.40 (.0005)
Dlco%
Baseline	−0.21 (.048)	−0.43 (< .0001)	−0.20 (.06)	−0.33 (.002)
6 mo	−0.30 (.006)	−0.49 (< .0001)	−0.34 (.002)	−0.45 (< .0001)
12 mo	−0.17 (.14)	−0.54 (< .0001)	−0.33 (.005)	−0.41 (.0004)
6MWD
Baseline	−0.14 (.19)	−0.36 (.0005)	−0.13 (.23)	−0.23 (.03)
6 mo	−0.28 (.01)	−0.45 (< .0001)	−0.37 (.0006)	−0.46 (< .0001)
12 mo	−0.20 (.08)	−0.49 (< .0001)	−0.37 (.001)	−0.41 (.0003)
Log(VEGF-D)
Baseline	0.09 (.42)	0.23 (.03)	0.18 (.10)	0.23 (.03)
6 mo	0.21 (.07)	0.27 (.02)	0.10 (.37)	0.19 (.09)
12 mo	0.19 (.12)	0.23 (.06)	0.15 (.20)	0.21 (.08)

Values are Spearman correlation coefficients (P value). See Table 1 legend for expansion of abbreviations.